Type III Thyroplasty for Patients With High-Pitched Voice Disorders: A Systematic Review and Meta-analysis.

IF 2.6 3区医学 Q1 OTORHINOLARYNGOLOGY Otolaryngology- Head and Neck Surgery Pub Date : 2025-02-27 DOI:10.1002/ohn.1185

Bruno Dalla Vecchia Vendramini, Lucas Marinho Siqueira Campos, Bruno Teixeira de Moraes, Silvio José de Vasconcelos, Mateus Morais Aires

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引用次数: 0

Abstract

Objective: High-pitched voice disorders can present notable social and professional obstacles for cisgender and transgender men. Our study aims to conduct a comprehensive meta-analysis assessing the efficacy of type III thyroplasty, also known as relaxation thyroplasty, for different populations with high-pitched voice disorders.

Data sources: A systematic literature review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, searching Medline/Pubmed, Embase, Cochrane, Science Direct, Scielo, LILACS, and Google Scholar databases from inception to April 2024.

Review methods: Studies included patients undergoing type III thyroplasty for high-pitched voice disorders. The primary outcome was the change in fundamental frequency postintervention. Subgroup analyses compared the following: (1) cisgender versus transgender populations, (2) primary versus secondary causes of high-pitched voice disorders, and (3) unilateral versus bilateral vertical stripe resection techniques.

Results: The initial search yielded 284 articles, 9 studies, including 69 unique patients, were included in the analysis. All studies provided level 4 evidence. Most patients were cisgender men with primary mutational dysphonia (66.7%, n = 46). The meta-analysis showed a significant reduction in fundamental frequency after surgery, with a mean difference of -75.9 Hz (95% confidence interval [CI]: -91.5 to -60.3). Cisgender men and patients submitted to unilateral resection had higher preoperative fundamental frequency and showed a more pronounced reduction in fundamental frequency. There were no significant differences between primary and secondary mutational dysphonia.

Conclusion: Type III thyroplasty effectively lowers vocal pitch in patients with high-pitched voice disorders. The procedure is viable for both cisgender and transgender men, as well as for primary and secondary voice disorders.

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来源期刊

Otolaryngology- Head and Neck Surgery 医学-耳鼻喉科学

CiteScore

6.70

自引率

2.90%

发文量

250

审稿时长

2-4 weeks

期刊介绍： Otolaryngology–Head and Neck Surgery (OTO-HNS) is the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation. The mission of Otolaryngology–Head and Neck Surgery is to publish contemporary, ethical, clinically relevant information in otolaryngology, head and neck surgery (ear, nose, throat, head, and neck disorders) that can be used by otolaryngologists, clinicians, scientists, and specialists to improve patient care and public health.