{"title":"Synchronous thyroid medullary cancer and thyroid hemiagenesis: A case report.","authors":"Chunyang Li, Chengbin Zhang, Chao Ma, Yonghui Wang, Quanhong Duan","doi":"10.3892/etm.2025.12827","DOIUrl":null,"url":null,"abstract":"<p><p>Thyroid hemiagenesis (TH) is a rare, congenital malformation defined as the absence of one thyroid lobe with or without an isthmus. By contrast, medullary thyroid cancer (MTC) is a rare thyroid malignancy, arises from parafollicular C cells. In the current study, a 33-year-old man presented with a small mass on the left side of the neck. Ultrasonography indicated a hyperechoic nodule in the left lobe of the thyroid gland and the right thyroid lobe could not be visualized. The patient underwent fine-needle aspiration cytology and MTC was suspected. The patient underwent total thyroidectomy, bilateral central lymph node dissection and left cervical compartment dissection. L-thyroxine (100 µg/per day) commenced immediately following thyroidectomy. During follow-up (monitored every 3 months), the patient remained healthy with no evidence of recurrence.</p>","PeriodicalId":94002,"journal":{"name":"Experimental and therapeutic medicine","volume":"29 4","pages":"77"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11862802/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental and therapeutic medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3892/etm.2025.12827","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Thyroid hemiagenesis (TH) is a rare, congenital malformation defined as the absence of one thyroid lobe with or without an isthmus. By contrast, medullary thyroid cancer (MTC) is a rare thyroid malignancy, arises from parafollicular C cells. In the current study, a 33-year-old man presented with a small mass on the left side of the neck. Ultrasonography indicated a hyperechoic nodule in the left lobe of the thyroid gland and the right thyroid lobe could not be visualized. The patient underwent fine-needle aspiration cytology and MTC was suspected. The patient underwent total thyroidectomy, bilateral central lymph node dissection and left cervical compartment dissection. L-thyroxine (100 µg/per day) commenced immediately following thyroidectomy. During follow-up (monitored every 3 months), the patient remained healthy with no evidence of recurrence.