Patient-Reported Outcomes of Pain and Related Quality of Life 1 Year After Bone-Anchored Limb Implantation in Patients with Lower-Limb Amputation.

Abstract

Background: Patients with lower-extremity amputations experience various pain types. Osseointegration allows for prosthesis wear through a bone-anchored implant. Patient-reported outcome measures following osseointegration have not been well studied. Our aim was to evaluate differences in pain and quality of life at 1 year after osseointegration of a bone-anchored limb.

Methods: We analyzed the severity and types of pain as measured by validated patient-reported outcome measures. Data were compared between the initial visit and the 1-year postoperative visit.

Results: Fifty-four patients were included in this study and demonstrated improvement in pain intensity as measured by the Numeric Rating Scale (p < 0.001) and Patient-Reported Outcomes Measurement Information System Global Health (PROMIS-GH) (p < 0.001), as well as residual limb pain when walking (p < 0.001), at 1 year postoperatively. The self-reported impact of pain on quality of life improved in both transfemoral and transtibial amputees (p < 0.001).

Conclusions: The osseointegration of a bone-anchored limb improved patient-reported pain and quality of life in lower-extremity amputees.

Level of evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.