Telemedicine for the Management of Neuropsychiatric Symptoms in Patients With Dementia Living in Long Term Care Facilities: Secondary and Exploratory Analyses From the DETECT Interventional Pilot Study

IF 3.8 2区 医学 Q1 GERIATRICS & GERONTOLOGY American Journal of Geriatric Psychiatry Pub Date : 2025-08-01 Epub Date: 2025-02-08 DOI:10.1016/j.jagp.2025.01.012
Adélaïde de Mauleon Ph.D. , Antoine Piau Ph.D. , Marion Baziard M.D. , Clive Ballard Ph.D. , Pascal Saidlitz M.D. , Thierry Voisin M.D. , Pierre Rumeau M.D. , Achille Tchalla Ph.D. , Christelle Cantet M.Sc. , Fati Nourashemi Ph.D. , Benoît Lepage Ph.D. , Maria Soto Ph.D.
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Abstract

Objective

This study aimed to compare the effects of telemedicine use in management of neuropsychiatric symptoms (NPS) in patients with dementia in long-term care facilities (LTCFs) versus usual care.

Design

DETECT is a prospective randomized controlled cluster pilot study with two arms: "usual care" and "intervention arm" utilizing telemedicine for NPS management. Our study includes secondary and exploratory analyses from the DETECT study (primary analyses were the subject of a separate publication).

Setting

Nineteen LTCFs participated. Patient outcomes included total hospitalizations including emergency room admittance, psychotropic drug prescriptions, NPS based on NPI-NH, quality of life based on QolAD, and functional status based on Activity Daily Living (ADL).

Measurements

Analyses were conducted on a modified intention-to-treat population. Mixed models were used for outcome measures, considering data correlation over time and intra-LTCF correlation.

Results

One hundred forty-one patients were included: 65 in the control group and 76 in the intervention group, 99 women (70.2%) with a mean age of 86.8 years ± 6.6 (SD). No difference was identified regarding hospitalizations and psychotropic drug prescriptions in the intervention group. During exploratory analyses, telemedicine showed significant improvement in the intervention group for NPI frequency × severity score (p = 0.001), NPI distress score (p = 0.03), ADL (p = 0.006), and several quality-of-life items compared to usual care.

Conclusions

Secondary analyses form DETECT study show no difference in the use of telemedicine on management of NPS in patients with dementia in LTCFs, in terms of hospitalizations and psychotropic drug prescription. However, some exploratory analyses indicated a positive effect of Telemedicine, including severity, frequency, distress, and functional autonomy compared to usual care.
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远程医疗对长期护理机构中痴呆患者神经精神症状的管理:来自DETECT介入试点研究的二次和探索性分析
目的:本研究旨在比较远程医疗在长期护理机构(ltcf)与常规护理中对痴呆患者神经精神症状(NPS)管理的影响。设计:DETECT是一项前瞻性随机对照集群先导研究,分为两组:“常规护理组”和“干预组”,利用远程医疗进行NPS管理。我们的研究包括来自DETECT研究的次要和探索性分析(主要分析是另一篇出版物的主题)。设置:共有19个ltcf参与。患者结局包括急诊住院总次数、精神药物处方、基于NPI-NH的NPS、基于QolAD的生活质量和基于活动日常生活(ADL)的功能状态。测量方法:对改良意向治疗人群进行分析。考虑到数据随时间的相关性和ltcf内部相关性,结果测量使用混合模型。结果:共纳入141例患者:对照组65例,干预组76例,女性99例(70.2%),平均年龄86.8岁±6.6 (SD)。干预组在住院和精神药物处方方面没有发现差异。在探索性分析中,与常规护理相比,远程医疗显示干预组在NPI频率×严重程度评分(p = 0.001)、NPI痛苦评分(p = 0.03)、ADL (p = 0.006)和一些生活质量项目上有显著改善。结论:DETECT研究的二次分析显示,在住院和精神药物处方方面,远程医疗在ltcf中痴呆患者NPS管理中的使用没有差异。然而,一些探索性分析表明,与常规护理相比,远程医疗的积极作用包括严重程度、频率、痛苦和功能自主。
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来源期刊
CiteScore
13.00
自引率
4.20%
发文量
381
审稿时长
26 days
期刊介绍: The American Journal of Geriatric Psychiatry is the leading source of information in the rapidly evolving field of geriatric psychiatry. This esteemed journal features peer-reviewed articles covering topics such as the diagnosis and classification of psychiatric disorders in older adults, epidemiological and biological correlates of mental health in the elderly, and psychopharmacology and other somatic treatments. Published twelve times a year, the journal serves as an authoritative resource for professionals in the field.
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