Lobectomy for Papillary Thyroid Carcinoma With Minimal Extrathyroidal Extension: Does the Site of Extension Matter?

IF 2.3 3区医学 Q1 OTORHINOLARYNGOLOGY Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-02-28 DOI:10.1002/hed.28113

Anner Moskovitz, Nir Tsur, Keren Kaminer, Dean Dudkiewicz, Eyal Robenshtok

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Abstract

Background: There is limited data on the recurrence risk following lobectomy in patients with microscopic extrathyroidal extension (mETE) and the significance of the site of mETE.

Methods: A retrospective study on patients treated with thyroid lobectomy between January 2012 and December 2023.

Results: Sixty-seven patients with papillary thyroid carcinoma (PTC) and mETE were included. Two patients (4.66%) experienced disease recurrence during a mean follow-up of 50 months (IQR 18.8-70.3). Twenty-five patients (37.3%) had anterior extension, 28 (41.8%) posterior, and 14 (20.9%) unknown location. Tumors with posterior extension had a higher rate of tall-cell variant (23.1% vs. 12%) and fewer positive surgical margins (22.2% vs. 37.5%). Three non-disease-related deaths occurred during follow-up. No recurrences were noted in patients with anterior mETE.

Conclusion: The recurrence risk after hemithyroidectomy for PTC with mETE was 4.66%, consistent with low-risk disease. Posterior mETE demonstrated a trend of a more aggressive variant and a higher recurrence rate.

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来源期刊

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 医学-耳鼻喉科学

CiteScore

7.00

自引率

6.90%

发文量

278

审稿时长

1.6 months

期刊介绍： Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.