{"title":"DNA Binding Affinities and Antimicrobial Activities of Pd(II) Complexes of Chromone Schiff Bases","authors":"Ameena Husain, B. Anupama, Ayub Shaik, Alia Begum","doi":"10.1002/aoc.70095","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Palladium complexes of the novel halogenated Schiff bases bearing chromone and antipyrine heterocyclic rings were conventionally synthesized. Their structural characterization was done by mass spectrometry, FT-IR, electronic, and <sup>1</sup>H-NMR spectral techniques. The metal complex stoichiometry was found to be 1:1 having a square planar geometry. The intercalative binding between CT-DNA and the novel palladium complexes was investigated by using absorption, emission spectroscopy, and viscometry. These complexes also revealed antibacterial activity against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> and antifungal activity against <i>Macrophomena</i> species.</p>\n </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Organometallic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/aoc.70095","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Palladium complexes of the novel halogenated Schiff bases bearing chromone and antipyrine heterocyclic rings were conventionally synthesized. Their structural characterization was done by mass spectrometry, FT-IR, electronic, and 1H-NMR spectral techniques. The metal complex stoichiometry was found to be 1:1 having a square planar geometry. The intercalative binding between CT-DNA and the novel palladium complexes was investigated by using absorption, emission spectroscopy, and viscometry. These complexes also revealed antibacterial activity against Escherichia coli and Staphylococcus aureus and antifungal activity against Macrophomena species.
期刊介绍：
All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.
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