Medication Adherence and Illness Perception in Patients with Rheumatoid Arthritis: The Mediating Effect of Self-Efficacy.

IF 1.7 4区 医学 Q4 NEUROSCIENCES Journal of musculoskeletal & neuronal interactions Pub Date : 2025-03-01 DOI:10.22540/JMNI-25-101
Lei Huang, Yang Zhou, Yan Liu, Peijun Xu, Xiaohong Deng
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引用次数: 0

Abstract

Objectives: To explore the mediating effect of self-efficacy (SE) on the relationship between medication adherence (MA) and illness perception (IP) in patients with rheumatoid arthritis (RA).

Methods: A convenient sampling method was used to select 238 RA patients undergoing treatment at two hospitals in Guangzhou, China. A cross-sectional survey was conducted, utilizing a general information questionnaire, a chronic disease SE scale, an IP scale, and the Medication Adherence Rating Scale (MARS-A). R software (Version 4.2.2) was used to construct a mediation model to examine the impact of SE and IP on MA among RA patients. The bootstrap method was employed to validate the mediating role of SE.

Results: The average scores for IP, SE, and MA were 120.50 ± 12.32, 29.36 ± 8.49, and 21.22 ± 2.96, respectively. Pearson correlation analysis revealed that SE was positively correlated with IP (r = 0.23, p < 0.01) and MA (r = 0.195, p < 0.001). IP was also positively correlated with MA (r = 0.532, p < 0.05). The mediating effect of SE in the relationship between IP and MA was confirmed.

Conclusion: SE partially mediates the relationship between IP and MA in patients with RA.

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来源期刊
CiteScore
3.40
自引率
0.00%
发文量
67
审稿时长
>12 weeks
期刊介绍: The Journal of Musculoskeletal and Neuronal Interactions (JMNI) is an academic journal dealing with the pathophysiology and treatment of musculoskeletal disorders. It is published quarterly (months of issue March, June, September, December). Its purpose is to publish original, peer-reviewed papers of research and clinical experience in all areas of the musculoskeletal system and its interactions with the nervous system, especially metabolic bone diseases, with particular emphasis on osteoporosis. Additionally, JMNI publishes the Abstracts from the biannual meetings of the International Society of Musculoskeletal and Neuronal Interactions, and hosts Abstracts of other meetings on topics related to the aims and scope of JMNI.
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