Stereoselective synthesis of allylic sulfones via palladium-catalyzed hydrosulfonylation of cyclopropenes

IF 4.6 1区化学 Q1 CHEMISTRY, ORGANIC Organic Chemistry Frontiers Pub Date : 2025-03-04 DOI:10.1039/d5qo00062a

Suliang Wang, Xuening Li, Jian Song, Xianjie Fang

引用次数: 0

Abstract

A novel efficient approach for obtaining allylic sulfones was demonstrated via palladium-catalyzed hydrosulfonylation of cyclopropenes. Preliminary mechanistic studies disclosed that π-allyl palladium might be the key intermediate. This process is applicable for a broad range of cyclopropane derivatives, and employs commercially available sodium sulfinates as sulfonyl source. Gram-scale reactions and further derivatizations showed the great synthetic potential of this method for construction of allylic sulfones.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

求助全文

约1分钟内获得全文去求助

来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.