WITHDRAWN: Effects of Deinorgestrel Treatment of Endometriosis on Ovarian Function, Inflammatory Factors, and Pregnancy Rate in Patients.

IF 4.7 3区 医学 Q1 PHARMACOLOGY & PHARMACY European journal of pharmacology Pub Date : 2025-03-01 DOI:10.1016/j.ejphar.2025.177440
Na Zhang, Zeming Li
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Abstract

This article has been withdrawn at the request of the author(s) and/or editor due to an error in the publishing process. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies-and-standards/article-withdrawal.

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去诺孕酮治疗子宫内膜异位症对卵巢功能、炎症因子及妊娠率的影响。
目的:比较去炔诺孕酮与桂芝茯苓胶囊对子宫内膜异位症患者卵巢功能、炎症指标及受孕率的影响。方法:90例子宫内膜异位症患者分为对照组和试验组。对照组患者口服桂芝茯苓胶囊,试验组患者口服地诺孕酮片。结果:与对照组比较,试验组总有效率明显提高。干预后,实验组的白细胞介素-6 (IL-6)和肿瘤坏死因子-α (TNF-α)水平明显低于对照组。治疗后痛经、性交困难和非经期下腹不适的视觉模拟评分(VAS)值均明显低于治疗前。与对照组相比,试验组痛经、非经期下腹疼痛和性交不适的VAS评分明显增加。与对照组相比,试验组1年累计妊娠率显著增高(42.22% (19/45)vs. 64.44%(29/45))。结论:Denogestone可显著缓解子宫内膜异位症患者的临床症状和机体炎症状态,且对卵巢功能无损害。
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来源期刊
CiteScore
9.00
自引率
0.00%
发文量
572
审稿时长
34 days
期刊介绍: The European Journal of Pharmacology publishes research papers covering all aspects of experimental pharmacology with focus on the mechanism of action of structurally identified compounds affecting biological systems. The scope includes: Behavioural pharmacology Neuropharmacology and analgesia Cardiovascular pharmacology Pulmonary, gastrointestinal and urogenital pharmacology Endocrine pharmacology Immunopharmacology and inflammation Molecular and cellular pharmacology Regenerative pharmacology Biologicals and biotherapeutics Translational pharmacology Nutriceutical pharmacology.
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