Lactate concentration increase in female college students with idiopathic scoliosis: A cross-sectional study.

IF 2.2 4区 医学 Q3 PHYSIOLOGY Physiology international Pub Date : 2025-03-04 Print Date: 2025-03-27 DOI:10.1556/2060.2025.00501
Nawanto Agung Prastowo, Maria Karen Tjhin, Mariani Santosa, Julia Rahadian Tanjung, Ignatio Rika Haryono
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引用次数: 0

Abstract

Purpose: Scoliosis may create muscle imbalance and disturb muscle metabolism. However, no studies have examined muscle cell metabolism in scoliosis. This study evaluates lactate concentration in female college students with scoliosis.

Methods: One hundred fifty female college students followed this cross-sectional analytic study. Inclusion and exclusion criteria were applied. Scoliosis was measured using a scoliometer. A scoliometer reading of 5° was considered scoliosis. Lactate concentration was measured using a lactate analyzer, and a lactate value above 2 mg dL-1 was denoted as 'elevated.' Anova and post hoc tests were used to analyze differences in the variables between scoliosis and normal subgroups. The results were significant if P < 0.05.

Results: One hundred participants (66.7%) had a spinal curve angle of more than 5°. Only weight in thoracic scoliosis was lower than normal (P = 0.022). Lactate was significantly higher than normal in all scoliosis subtypes (P < 0.001). Lactate in both types was considerably higher than thoracic and lumbar scoliosis (P = 0.04 and 0.03, respectively).

Conclusion: Lactate concentration increased in female students with scoliosis.

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特发性脊柱侧凸女大学生乳酸浓度升高:横断面研究。
目的:脊柱侧凸可造成肌肉失衡,扰乱肌肉代谢。然而,没有研究检查脊柱侧凸的肌肉细胞代谢。本研究评估女大学生脊柱侧凸患者乳酸浓度。方法:对150名女大学生进行横断面分析研究。采用纳入和排除标准。使用脊柱侧凸计测量脊柱侧凸。脊柱侧弯计读数为5°被认为是脊柱侧弯。使用乳酸分析仪测量乳酸浓度,乳酸值高于2 mg dL-1表示“升高”。采用方差分析和事后检验来分析脊柱侧凸和正常亚组之间变量的差异。P < 0.05,结果有显著性意义。结果:100例(66.7%)患者脊柱弯曲角度大于5°。仅胸椎侧凸组体重低于正常组(P = 0.022)。乳酸水平在所有脊柱侧凸亚型中均显著高于正常水平(P < 0.001)。两种类型的乳酸水平均明显高于胸椎和腰椎侧凸(P值分别为0.04和0.03)。结论:女学生脊柱侧凸患者乳酸浓度增高。
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来源期刊
Physiology international
Physiology international Medicine-Physiology (medical)
CiteScore
3.40
自引率
0.00%
发文量
37
期刊介绍: The journal provides a forum for important new research papers written by eminent scientists on experimental medical sciences. Papers reporting on both original work and review articles in the fields of basic and clinical physiology, pathophysiology (from the subcellular organization level up to the oranizmic one), as well as related disciplines, including history of physiological sciences, are accepted.
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