Application of spectroscopic technology with machine learning in Chinese herbs from seeds to medicinal materials: The case of genus Paris.

IF 8.9 Journal of pharmaceutical analysis Pub Date : 2025-02-01 Epub Date: 2024-09-13 DOI:10.1016/j.jpha.2024.101103
Yangna Feng, Xinyan Zhu, Yuanzhong Wang
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Abstract

To ensure the safety and efficacy of Chinese herbs, it is of great significance to conduct rapid quality detection of Chinese herbs at every link of their supply chain. Spectroscopic technology can reflect the overall chemical composition and structural characteristics of Chinese herbs, with the multi-component and multitarget characteristics of Chinese herbs. This review took the genus Paris as an example, and applications of spectroscopic technology with machine learning (ML) in supply chain of the genus Paris from seeds to medicinal materials were introduced. The specific contents included the confirmation of germplasm resources, identification of growth years, cultivar, geographical origin, and original processing and processing methods. The potential application of spectroscopic technology in genus Paris was pointed out, and the prospects of combining spectroscopic technology with blockchain were proposed. The summary and prospects presented in this paper will be beneficial to the quality control of the genus Paris in all links of its supply chain, so as to rationally use the genus Paris resources and ensure the safety and efficacy of medication.

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光谱技术与机器学习在中草药从种子到药材中的应用:以巴黎属为例。
为了保证中药材的安全性和有效性,对中药材供应链的各个环节进行快速的质量检测具有重要意义。光谱技术可以反映中草药的整体化学成分和结构特征,具有中草药多成分、多靶点的特点。本文以巴黎属植物为例,介绍了光谱技术与机器学习(ML)在巴黎属植物从种子到药材供应链中的应用。具体内容包括种质资源的确认、生长年限、品种、产地、原产加工和加工方法的鉴定。指出了光谱学技术在巴黎属植物中的应用前景,并展望了光谱学技术与区块链结合的前景。本文的总结和展望,将有利于巴黎属在其供应链各环节的质量控制,从而合理利用巴黎属资源,保证用药的安全性和有效性。
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