Eduardo Fonseca-Pedrero, Alicia Pérez-Albéniz, Beatriz Lucas-Molina, Susana Al-Halabí, Martin Debbané
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引用次数: 0
Abstract
Background New theoretical and measurement models related to Bayesian networks can usefully be implemented to enrich our understanding of psychosis risk. The present study aims to explore, using a directed acyclic graph (DAG), the putative causal relationship within schizotypal facets, as well as between schizotypal dimensions, psychopathology, and reflective functioning (RF) impairments, in a representative sample of non-clinical adolescents. Study Design A sample of 1476 adolescents from the general population participated in a cross-sectional survey. The Oviedo Schizotypy Assessment Questionnaire-Revised, the Strengths and Difficulties Questionnaire, and the Reflective Functioning Questionnaire (RFQ) were used. Study Results Schizotypal traits were positively associated with psychopathology and hypomentalizing. Putative causal relationships are presented between Reality distortion, Social disorganization, and Anhedonia. In addition, estimated DAG suggests that schizotypal dimensions influence psychopathology and RF impairments. Conclusions The findings suggest different pathways connecting schizotypal traits, mental health problems, and RF impairments during adolescence. The use of probabilistic DAG may allow us to make more robust conclusions about the direction of causation and to unravel potentially complex causal chains in the study of psychosis risk.
背景与贝叶斯网络相关的新理论和测量模型可以有效地丰富我们对精神病风险的理解。本研究的目的是利用有向无环图(DAG),在非临床青少年的代表性样本中,探讨精神分裂分型面之间的推定因果关系,以及精神分裂分型维度、精神病理学和反思功能(RF)障碍之间的推定因果关系。研究设计 共有1476名青少年参加了横断面调查。调查使用了奥维多分裂型评估问卷-修订版、优势与困难问卷和反思功能问卷(RFQ)。研究结果 人格分裂型特质与精神病理学和妄想症呈正相关。现实扭曲、社会混乱和失恋之间存在推测的因果关系。此外,估计的 DAG 表明,精神分裂症维度会影响精神病理学和射频损伤。结论 研究结果表明,青春期精神分裂症特质、心理健康问题和射频损伤之间存在不同的联系。使用概率 DAG 可以让我们对因果关系的方向做出更可靠的结论,并在研究精神病风险时解开潜在的复杂因果链。
期刊介绍:
Schizophrenia Bulletin seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia. We view the field as broad and deep, and will publish new knowledge ranging from the molecular basis to social and cultural factors. We will give new emphasis to translational reports which simultaneously highlight basic neurobiological mechanisms and clinical manifestations. Some of the Bulletin content is invited as special features or manuscripts organized as a theme by special guest editors. Most pages of the Bulletin are devoted to unsolicited manuscripts of high quality that report original data or where we can provide a special venue for a major study or workshop report. Supplement issues are sometimes provided for manuscripts reporting from a recent conference.