A multi-stage fusion deep learning framework merging local patterns with attention-driven contextual dependencies for cancer detection

IF 6.3 2区 医学 Q1 BIOLOGY Computers in biology and medicine Pub Date : 2025-05-01 Epub Date: 2025-03-06 DOI:10.1016/j.compbiomed.2025.109916
Hatice Catal Reis , Veysel Turk
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Abstract

Cancer is a severe threat to public health. Early diagnosis of disease is critical, but the lack of experts in this field, the personal assessment process, the clinical workload, and the high level of similarity in disease classes make it difficult. In recent years, deep learning-based artificial intelligence models have shown promise, with the potential to increase diagnosis speed and accuracy. These models attract attention with their automatic learning and adaptation capabilities. In this study, the deep learning-based PADBSRNet model and the PADBSRNet-Vision Transformer (ViT) hybrid method are proposed for the detection of brain tumors and skin and lung cancers. PADBSRNet is a comprehensive deep neural network architecture that integrates separable and traditional convolution layers, multiple attention mechanisms, bidirectional recurrent neural networks, and cross-connections/multi-stage feature fusion strategies. This architecture offers significant advantages in terms of effectively extracting local-global, contextual features and accurately modeling long-term dependencies in image classification tasks. The second proposed approach developed a hybrid method that combines the advantages of the PADBSRNet model and the ViT model. Experimental analysis on medical datasets such as the Figshare Brain Tumor Dataset, IQ-OTH/NCCD Dataset, and Skin Cancer: Malignant vs. Benign Dataset has evaluated the proposed models' performances. According to the experimental results, the PADBSRNet model has shown successful performance with 95.24 %, 99.55 %, and 88.61 % accuracy rates, respectively. The experimental findings show that the proposed deep learning model can effectively learn the complex relationships and hidden patterns of cancer disease, thus producing applicable and effective results in cancer diagnosis.
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一种多阶段融合深度学习框架,将局部模式与注意力驱动的上下文依赖相结合,用于癌症检测
癌症是对公众健康的严重威胁。疾病的早期诊断是至关重要的,但缺乏这一领域的专家,个人评估过程,临床工作量以及疾病类别的高度相似性使其变得困难。近年来,基于深度学习的人工智能模型已经显示出前景,有可能提高诊断速度和准确性。这些模型以其自动学习和适应能力吸引了人们的注意。本研究提出了基于深度学习的PADBSRNet模型和PADBSRNet- vision Transformer (ViT)混合方法用于脑肿瘤、皮肤癌和肺癌的检测。PADBSRNet是一种综合的深度神经网络架构,它集成了可分离层和传统卷积层、多注意机制、双向递归神经网络以及交叉连接/多阶段特征融合策略。该体系结构在有效提取局部-全局、上下文特征和准确建模图像分类任务中的长期依赖关系方面具有显著优势。第二种方法开发了一种混合方法,结合了PADBSRNet模型和ViT模型的优点。在Figshare脑肿瘤数据集、IQ-OTH/NCCD数据集和皮肤癌:恶性与良性数据集等医学数据集上的实验分析评估了所提出模型的性能。实验结果表明,PADBSRNet模型的准确率分别为95.24%、99.55%和88.61%。实验结果表明,所提出的深度学习模型可以有效地学习癌症疾病的复杂关系和隐藏模式,从而在癌症诊断中产生适用和有效的结果。
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来源期刊
Computers in biology and medicine
Computers in biology and medicine 工程技术-工程:生物医学
CiteScore
11.70
自引率
10.40%
发文量
1086
审稿时长
74 days
期刊介绍: Computers in Biology and Medicine is an international forum for sharing groundbreaking advancements in the use of computers in bioscience and medicine. This journal serves as a medium for communicating essential research, instruction, ideas, and information regarding the rapidly evolving field of computer applications in these domains. By encouraging the exchange of knowledge, we aim to facilitate progress and innovation in the utilization of computers in biology and medicine.
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