{"title":"Speed and accuracy in Tandem: Deep Learning-Powered Millisecond-Level pulmonary embolism detection in CTA","authors":"Houde Wu , Ting Chen , Longshuang Wang , Li Guo","doi":"10.1016/j.bspc.2025.107792","DOIUrl":null,"url":null,"abstract":"<div><h3>Background and Objectives</h3><div>Pulmonary embolism (PE) is a critical medical condition that requires a rapid and accurate diagnosis. Traditional methods, although highly precise, have focused primarily on accuracy, neglecting the urgency of speed required in emergency settings. This study aims to develop a deep learning model that not only maintains high accuracy but also achieves millisecond-level PE detection speed.</div></div><div><h3>Materials and Methods</h3><div>This study employed an internal dataset comprising 160 patients from Tianjin Medical University General Hospital, and an external RSNA dataset for validation. Our model, built upon the YOLOv5 framework, was enhanced with Partial Convolution, a C2f module, and decoupled head structure.</div></div><div><h3>Results</h3><div>The internal test set achieved a recall of 82.5 %, precision of 84.2 %, and mean average precision (mAP) of 87.2 %, significantly outperforming the other leading models. Notably, our model provided an inference time of just 1.6 ms per image, setting a new benchmark for real-time PE detection, which was faster than YOLOv5 (2.9 ms), YOLOv6 (4.0 ms), and YOLOv8 (3.2 ms). Furthermore, our model demonstrated faster convergence and consistently lower loss values during training, achieving perfect precision at a significantly lower confidence threshold than other YOLO variants, highlighting its superior optimization and generalization capabilities.</div></div><div><h3>Conclusion</h3><div>This study successfully developed a deep learning model capable of millisecond-level PE detection without compromising the accuracy. Its performance underscores its potential to revolutionize PE diagnosis in emergency clinical settings, enabling timely and reliable intervention.</div></div>","PeriodicalId":55362,"journal":{"name":"Biomedical Signal Processing and Control","volume":"106 ","pages":"Article 107792"},"PeriodicalIF":4.9000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Signal Processing and Control","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1746809425003039","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background and Objectives
Pulmonary embolism (PE) is a critical medical condition that requires a rapid and accurate diagnosis. Traditional methods, although highly precise, have focused primarily on accuracy, neglecting the urgency of speed required in emergency settings. This study aims to develop a deep learning model that not only maintains high accuracy but also achieves millisecond-level PE detection speed.
Materials and Methods
This study employed an internal dataset comprising 160 patients from Tianjin Medical University General Hospital, and an external RSNA dataset for validation. Our model, built upon the YOLOv5 framework, was enhanced with Partial Convolution, a C2f module, and decoupled head structure.
Results
The internal test set achieved a recall of 82.5 %, precision of 84.2 %, and mean average precision (mAP) of 87.2 %, significantly outperforming the other leading models. Notably, our model provided an inference time of just 1.6 ms per image, setting a new benchmark for real-time PE detection, which was faster than YOLOv5 (2.9 ms), YOLOv6 (4.0 ms), and YOLOv8 (3.2 ms). Furthermore, our model demonstrated faster convergence and consistently lower loss values during training, achieving perfect precision at a significantly lower confidence threshold than other YOLO variants, highlighting its superior optimization and generalization capabilities.
Conclusion
This study successfully developed a deep learning model capable of millisecond-level PE detection without compromising the accuracy. Its performance underscores its potential to revolutionize PE diagnosis in emergency clinical settings, enabling timely and reliable intervention.
期刊介绍:
Biomedical Signal Processing and Control aims to provide a cross-disciplinary international forum for the interchange of information on research in the measurement and analysis of signals and images in clinical medicine and the biological sciences. Emphasis is placed on contributions dealing with the practical, applications-led research on the use of methods and devices in clinical diagnosis, patient monitoring and management.
Biomedical Signal Processing and Control reflects the main areas in which these methods are being used and developed at the interface of both engineering and clinical science. The scope of the journal is defined to include relevant review papers, technical notes, short communications and letters. Tutorial papers and special issues will also be published.