Speed and accuracy in Tandem: Deep Learning-Powered Millisecond-Level pulmonary embolism detection in CTA

IF 4.9 2区 医学 Q1 ENGINEERING, BIOMEDICAL Biomedical Signal Processing and Control Pub Date : 2025-08-01 Epub Date: 2025-03-05 DOI:10.1016/j.bspc.2025.107792
Houde Wu , Ting Chen , Longshuang Wang , Li Guo
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Abstract

Background and Objectives

Pulmonary embolism (PE) is a critical medical condition that requires a rapid and accurate diagnosis. Traditional methods, although highly precise, have focused primarily on accuracy, neglecting the urgency of speed required in emergency settings. This study aims to develop a deep learning model that not only maintains high accuracy but also achieves millisecond-level PE detection speed.

Materials and Methods

This study employed an internal dataset comprising 160 patients from Tianjin Medical University General Hospital, and an external RSNA dataset for validation. Our model, built upon the YOLOv5 framework, was enhanced with Partial Convolution, a C2f module, and decoupled head structure.

Results

The internal test set achieved a recall of 82.5 %, precision of 84.2 %, and mean average precision (mAP) of 87.2 %, significantly outperforming the other leading models. Notably, our model provided an inference time of just 1.6 ms per image, setting a new benchmark for real-time PE detection, which was faster than YOLOv5 (2.9 ms), YOLOv6 (4.0 ms), and YOLOv8 (3.2 ms). Furthermore, our model demonstrated faster convergence and consistently lower loss values during training, achieving perfect precision at a significantly lower confidence threshold than other YOLO variants, highlighting its superior optimization and generalization capabilities.

Conclusion

This study successfully developed a deep learning model capable of millisecond-level PE detection without compromising the accuracy. Its performance underscores its potential to revolutionize PE diagnosis in emergency clinical settings, enabling timely and reliable intervention.
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速度和准确性的串联:深度学习驱动的CTA毫秒级肺栓塞检测
背景与目的肺栓塞(PE)是一种需要快速准确诊断的危重疾病。传统方法虽然精度很高,但主要侧重于准确性,而忽略了紧急情况下所需的速度紧迫性。本研究旨在开发一种既保持高精度又达到毫秒级PE检测速度的深度学习模型。材料与方法本研究采用天津医科大学总医院160例患者的内部数据集和外部RSNA数据集进行验证。我们的模型建立在YOLOv5框架上,通过局部卷积、C2f模块和解耦头部结构进行了增强。结果内部测试集的查全率为82.5%,查准率为84.2%,平均查准率(mAP)为87.2%,显著优于其他主流模型。值得注意的是,我们的模型提供的每幅图像的推理时间仅为1.6 ms,为实时PE检测设定了新的基准,比YOLOv5 (2.9 ms), YOLOv6 (4.0 ms)和YOLOv8 (3.2 ms)更快。此外,我们的模型在训练过程中表现出更快的收敛速度和更低的损失值,在明显低于其他YOLO变体的置信阈值下实现了完美的精度,突出了其优越的优化和泛化能力。结论本研究成功开发了一种能够在不影响准确性的情况下进行毫秒级PE检测的深度学习模型。它的性能强调了它在紧急临床环境中彻底改变PE诊断的潜力,使及时和可靠的干预成为可能。
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来源期刊
Biomedical Signal Processing and Control
Biomedical Signal Processing and Control 工程技术-工程:生物医学
CiteScore
9.80
自引率
13.70%
发文量
822
审稿时长
4 months
期刊介绍: Biomedical Signal Processing and Control aims to provide a cross-disciplinary international forum for the interchange of information on research in the measurement and analysis of signals and images in clinical medicine and the biological sciences. Emphasis is placed on contributions dealing with the practical, applications-led research on the use of methods and devices in clinical diagnosis, patient monitoring and management. Biomedical Signal Processing and Control reflects the main areas in which these methods are being used and developed at the interface of both engineering and clinical science. The scope of the journal is defined to include relevant review papers, technical notes, short communications and letters. Tutorial papers and special issues will also be published.
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