Severe hemolytic anemia caused by paravalvular leak after transcatheter aortic valve replacement with a new-generation balloon-expandable transcatheter aortic valve requiring surgical aortic valve replacement
{"title":"Severe hemolytic anemia caused by paravalvular leak after transcatheter aortic valve replacement with a new-generation balloon-expandable transcatheter aortic valve requiring surgical aortic valve replacement","authors":"Jumpei Takeda , Akira Taruya , Teruaki Wada , Kentaro Honda , Ryo Hikida , Takahiro Nishi , Mizuho Ikuchi , Ryo Nakamura , Hideki Kunimoto , Kazushi Takemoto , Hironori Kitabata , Yoshiharu Nishimura , Atsushi Tanaka","doi":"10.1016/j.crmic.2025.100062","DOIUrl":null,"url":null,"abstract":"<div><div>Mechanical hemolysis is a rare complication following transcatheter aortic valve replacement (TAVR) and requires redo replacement surgery. We report a case of severe hemolytic anemia caused by a paravalvular leak (PVL) after TAVR requiring surgical aortic valve replacement (SAVR). A female in her 80s who underwent TAVR with a 20 mm balloon-expandable valve for symptomatic severe aortic stenosis developed severe uncontrollable hemolytic anemia as a result of a PVL originating from a tiny gap between the prosthetic valve and small calcifications of the left ventricular outflow tract. SAVR was performed, leading to resolution of hemolysis.</div></div>","PeriodicalId":100217,"journal":{"name":"Cardiovascular Revascularization Medicine: Interesting Cases","volume":"6 ","pages":"Article 100062"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular Revascularization Medicine: Interesting Cases","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2950275625000085","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Mechanical hemolysis is a rare complication following transcatheter aortic valve replacement (TAVR) and requires redo replacement surgery. We report a case of severe hemolytic anemia caused by a paravalvular leak (PVL) after TAVR requiring surgical aortic valve replacement (SAVR). A female in her 80s who underwent TAVR with a 20 mm balloon-expandable valve for symptomatic severe aortic stenosis developed severe uncontrollable hemolytic anemia as a result of a PVL originating from a tiny gap between the prosthetic valve and small calcifications of the left ventricular outflow tract. SAVR was performed, leading to resolution of hemolysis.