A review of recent advances in anesthetic drugs for patients undergoing cardiac surgery.

IF 4.8 2区 医学 Q1 PHARMACOLOGY & PHARMACY Frontiers in Pharmacology Pub Date : 2025-02-18 eCollection Date: 2025-01-01 DOI:10.3389/fphar.2025.1533162
Yutian Sun, Xiangyou Sun, Haibo Wu, Zhaoyang Xiao, Wei Luo
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Abstract

Inducing and maintaining general anesthesia requires a diverse set of medications. Currently, heart surgery anesthetic management does not adhere to any one standard protocol or set of drugs. To ensure steady circulatory function while providing sufficient sedation, anesthetic medications are carefully selected for cardiovascular operations. Among the opioids used most often in cardiac surgery are fentanyl, sufentanil, and remifentanil. As a cardiac anesthesiologist, your key responsibilities will be to maintain your patient's blood pressure (BP) and oxygen levels, reduce the frequency and intensity of ischemia events, and make it easy for them to get off of cardiopulmonary bypass (CPB) and supplemental oxygen fast. Additionally, new knowledge gaps have been identified as a result of developments in cardiac anesthetics, which must be addressed. The goal of the most recent developments in cardiac anesthesia has been to decrease risks and increase accuracy in patient outcomes during cardiac surgeries. Furthermore, new methods and tools are contributing to the evolution of cardiovascular anesthesia toward a more dynamic, patient-centered approach, with an eye on boosting safety, decreasing complications, and facilitating better recovery for patients. New medications and methods have emerged in the field of anesthetic pharmacology, aiming to improve anesthesia management, particularly for patients who have cardiovascular disease. Optimal cardiovascular stability, fewer side effects, and enhanced surgical recovery are achieved by use of these medications. We have reviewed all the different kinds of cardiac anesthetic techniques and medications in this research. We have also examined the many new anesthetic medicines that have been produced and used for individuals with cardiovascular issues. Next, we covered prospects in the realm of cardiovascular anesthesia and novel cardiac anesthetic drugs.

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心脏手术患者麻醉药物的最新进展综述。
诱导和维持全身麻醉需要多种药物。目前,心脏手术麻醉管理没有遵循任何一种标准方案或一套药物。为了确保稳定的循环功能,同时提供足够的镇静作用,心血管手术的麻醉药物是精心选择的。在心脏手术中最常用的阿片类药物是芬太尼、舒芬太尼和瑞芬太尼。作为一名心脏麻醉师,你的主要职责是维持病人的血压(BP)和氧气水平,减少缺血事件的频率和强度,并使他们能够轻松地快速脱离体外循环(CPB)和补充氧气。此外,由于心脏麻醉剂的发展,已经发现了新的知识空白,必须加以解决。心脏麻醉的最新发展目标是在心脏手术中降低风险和提高患者预后的准确性。此外,新的方法和工具正在促进心血管麻醉朝着更加动态、以患者为中心的方向发展,着眼于提高安全性、减少并发症和促进患者更好地康复。麻醉药理学领域出现了新的药物和方法,旨在改善麻醉管理,特别是对患有心血管疾病的患者。使用这些药物可达到最佳的心血管稳定性、较少的副作用和增强的手术恢复。我们回顾了本研究中所有不同种类的心脏麻醉技术和药物。我们还研究了许多已经生产并用于心血管疾病患者的新麻醉药物。接下来,我们讨论了心血管麻醉和新型心脏麻醉药物领域的前景。
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来源期刊
Frontiers in Pharmacology
Frontiers in Pharmacology PHARMACOLOGY & PHARMACY-
CiteScore
7.80
自引率
8.90%
发文量
5163
审稿时长
14 weeks
期刊介绍: Frontiers in Pharmacology is a leading journal in its field, publishing rigorously peer-reviewed research across disciplines, including basic and clinical pharmacology, medicinal chemistry, pharmacy and toxicology. Field Chief Editor Heike Wulff at UC Davis is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
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