FeMo6 integrated covalent organic frameworks: Peroxidase-mimetic colorimetric biosensors for multivariate sensing hydrogen peroxide and ascorbic acid in serum and beverages

IF 8.5 1区农林科学 Q1 CHEMISTRY, APPLIED Food Chemistry Pub Date : 2025-03-06 DOI:10.1016/j.foodchem.2025.143727

Xinyu Han, Jihong Zhou, Yunjie Li, Yuhan Zhao, Yanfei Li, Yingjie Hua, Taowen Dong, Fang Chai

{"title":"FeMo6 integrated covalent organic frameworks: Peroxidase-mimetic colorimetric biosensors for multivariate sensing hydrogen peroxide and ascorbic acid in serum and beverages","authors":"Xinyu Han, Jihong Zhou, Yunjie Li, Yuhan Zhao, Yanfei Li, Yingjie Hua, Taowen Dong, Fang Chai","doi":"10.1016/j.foodchem.2025.143727","DOIUrl":null,"url":null,"abstract":"An efficient and readable sensor is desirable for food safety and diagnosis. Herein, a homogeneous mimicking enzyme was constructed by encapsulating polyoxometalate (NH₄)₃[FeMo₆O₁₈(OH)₆]·6H₂O (FeMo6) into the covalent organic framework (FeMo6@COF). Coordinating the spatial confinement effect of COF, FeMo6 exhibited superior peroxide-like activity to catalyze H2O2 to •O− 2, which achieved the “on-off” consecutive sensing of H2O2 and AA via a readable colorimetric mode, with the limit of detection (LOD) at 30 μM and 0.35 μM, respectively. A convenient smartphone assistant platform was established and realized rapid, portable, visual monitoring of AA with LOD of 0.06 μM, and satisfied recoveries with 96.88–104.65 % in human serum and 98.37–107.61 % in commercial beverages. Furthermore, a logic gate circuit was designed to illustrate the potential utilization of combining the intelligent facilities with the experiment. This strategy provides efficient, swift, convenient sensor FeMo6@COF with great potential contribution in food safety and diagnosis.","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"46 1","pages":""},"PeriodicalIF":8.5000,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Chemistry","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1016/j.foodchem.2025.143727","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}

引用次数: 0

Abstract

An efficient and readable sensor is desirable for food safety and diagnosis. Herein, a homogeneous mimicking enzyme was constructed by encapsulating polyoxometalate (NH₄)₃[FeMo₆O₁₈(OH)₆]·6H₂O (FeMo₆) into the covalent organic framework (FeMo₆@COF). Coordinating the spatial confinement effect of COF, FeMo₆ exhibited superior peroxide-like activity to catalyze H₂O₂ to •O− 2, which achieved the “on-off” consecutive sensing of H₂O₂ and AA via a readable colorimetric mode, with the limit of detection (LOD) at 30 μM and 0.35 μM, respectively. A convenient smartphone assistant platform was established and realized rapid, portable, visual monitoring of AA with LOD of 0.06 μM, and satisfied recoveries with 96.88–104.65 % in human serum and 98.37–107.61 % in commercial beverages. Furthermore, a logic gate circuit was designed to illustrate the potential utilization of combining the intelligent facilities with the experiment. This strategy provides efficient, swift, convenient sensor FeMo₆@COF with great potential contribution in food safety and diagnosis.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

求助全文

约1分钟内获得全文去求助

来源期刊

Food Chemistry 工程技术-食品科技

CiteScore

16.30

自引率

10.20%

发文量

3130

审稿时长

122 days

期刊介绍： Food Chemistry publishes original research papers dealing with the advancement of the chemistry and biochemistry of foods or the analytical methods/ approach used. All papers should focus on the novelty of the research carried out.