Anandakumar Pandi, Balarko Chakraborty, Nabendu Sen, Vanitha Manickam Kalappan
{"title":"The hepatoprotective potential of ferulic acid against a spectrum of pharmaceuticals and toxic compounds","authors":"Anandakumar Pandi, Balarko Chakraborty, Nabendu Sen, Vanitha Manickam Kalappan","doi":"10.1007/s00204-025-03996-3","DOIUrl":null,"url":null,"abstract":"<div><p>Despite advancements in medicine, drug-induced liver injury continues to pose regulatory and clinical challenges. Ferulic acid, a naturally occurring polyphenol found in vegetables, fruits, and grains, has gained attention for its therapeutic properties. We report the hepatoprotective effects of ferulic acid against a range of pharmaceuticals and toxic compounds. Given the growing interest in natural hepatoprotective compounds, further research is essential to elucidate ferulic acid’s role in liver protection.</p></div>","PeriodicalId":8329,"journal":{"name":"Archives of Toxicology","volume":"99 5","pages":"2229 - 2234"},"PeriodicalIF":6.9000,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Toxicology","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00204-025-03996-3","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"TOXICOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Despite advancements in medicine, drug-induced liver injury continues to pose regulatory and clinical challenges. Ferulic acid, a naturally occurring polyphenol found in vegetables, fruits, and grains, has gained attention for its therapeutic properties. We report the hepatoprotective effects of ferulic acid against a range of pharmaceuticals and toxic compounds. Given the growing interest in natural hepatoprotective compounds, further research is essential to elucidate ferulic acid’s role in liver protection.
期刊介绍：
Archives of Toxicology provides up-to-date information on the latest advances in toxicology. The journal places particular emphasis on studies relating to defined effects of chemicals and mechanisms of toxicity, including toxic activities at the molecular level, in humans and experimental animals. Coverage includes new insights into analysis and toxicokinetics and into forensic toxicology. Review articles of general interest to toxicologists are an additional important feature of the journal.
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