Adherence and aerobic exercise intensity in live online exercise sessions for older adults with mild cognitive impairment: Insights from the Japan-Multimodal Intervention Trial for the Prevention of Dementia.

JAR life Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI:10.1016/j.jarlif.2025.100003
Taiki Sugimoto, Kazuaki Uchida, Yoko Yokoyama, Ayaka Onoyama, Kosuke Fujita, Yujiro Kuroda, Keigo Hinakura, Susumu Ogawa, Hiroyuki Suzuki, Yoshinori Fujiwara, Paul K Crane, Hidenori Arai, Takashi Sakurai
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Abstract

Background: Intervention adherence is crucial to ensure cognitive benefits in trials designed to prevent cognitive decline. During the coronavirus disease 2019 (COVID-19) pandemic, the Japan-Multimodal Intervention Trial for the Prevention of Dementia offered live online exercise sessions to older adults with mild cognitive impairment (MCI).

Objectives: To assess adherence and aerobic exercise intensity through live online exercise sessions in older adults with MCI.

Design: Posthoc analysis of the 18-month, multi-center, randomized controlled trial.

Setting: The study was conducted across five institutions in Japan.

Participants: Older adults aged 65-85 years who were assigned to the intervention group and completed the intervention. Participants were stratified by region (Aichi and Tokyo), where the state of emergency duration due to COVID-19 varied.

Interventions: The intervention group participated in multidomain interventions, including 90-minute group-based physical exercise sessions held weekly for 78 sessions. During the state of emergency, live online sessions were conducted via video conferencing.

Measurements: Attendance rates and aerobic exercise intensity (based on heart rates) during online and onsite sessions were compared using the Wilcoxon signed-rank test.

Results: A total of 207 participants were analyzed. Over 18 months, 78 exercise sessions were conducted, including live online sessions. In the Aichi region, 2 online sessions were held, while in the Tokyo region, 24 online sessions were conducted. In the Tokyo region, adherence was higher in online sessions compared to onsite sessions (92 % vs. 86 %, p = 0.046), while exercise intensity showed no significant difference (49 % vs. 52 %, p = 0.279). No adverse events were reported.

Conclusions: Live online exercise sessions were safe, feasible, and demonstrated adherence and intensity comparable to onsite sessions.

Trial registration: The trial was registered at the University Hospital Medical Information Network Clinical Trials Registry (UMIN-CTR) on November 24, 2019 (UMIN000038671) (https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000044075).

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轻度认知障碍老年人在线运动课程的依从性和有氧运动强度:来自日本预防痴呆多模式干预试验的见解
背景:在旨在预防认知能力下降的试验中,坚持干预对于确保认知获益至关重要。在2019冠状病毒病(COVID-19)大流行期间,日本预防痴呆症多模式干预试验为患有轻度认知障碍(MCI)的老年人提供了实时在线锻炼课程。目的:通过在线运动课程评估老年轻度认知损伤患者的依从性和有氧运动强度。设计:对18个月的多中心随机对照试验进行事后分析。环境:这项研究是在日本的五家机构进行的。参与者:65-85岁的老年人被分配到干预组并完成了干预。参与者按地区(爱知县和东京)分层,因COVID-19导致的紧急状态持续时间各不相同。干预措施:干预组参与多领域干预,包括每周进行78次90分钟的小组体育锻炼。在紧急状态期间,通过视频会议进行了在线直播会议。测量方法:使用Wilcoxon符号秩检验比较在线和现场会议期间的出勤率和有氧运动强度(基于心率)。结果:共分析了207名参与者。在18个月的时间里,他们进行了78次锻炼,包括在线直播。在爱知地区,举行了2次在线会议,而在东京地区,进行了24次在线会议。在东京地区,在线训练的坚持度高于现场训练(92%对86%,p = 0.046),而运动强度没有显著差异(49%对52%,p = 0.279)。无不良事件报告。结论:实时在线锻炼是安全、可行的,并且表现出与现场锻炼相当的依从性和强度。试验注册:该试验已于2019年11月24日在大学医院医学信息网络临床试验注册中心(UMIN-CTR)注册(UMIN000038671) (https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000044075)。
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