{"title":"Paclitaxel crystal visualization by intravascular imaging following drug-coated balloon angioplasty: A report of 2 cases","authors":"Rajesh Vijayvergiya, Arghadip Bose, Nikhil Sharma, Basant Kumar, Bhupinder K. Sihag, Ankush Gupta","doi":"10.1016/j.carrev.2025.02.013","DOIUrl":null,"url":null,"abstract":"<div><div>Drug-coated balloons (DCB) have evolved as an alternative to drug-eluting stents in coronary interventions without the addition of an extra metal layer while delivering antiproliferative drugs. However, the delivery of the drug at the target site cannot be objectively assessed in routine practice. Hence, the success of a DCB angioplasty is limited to luminal gain alone. We report a novel finding of tiny paclitaxel crystals detected on the intimal surface by intravascular ultrasound (IVUS) and optical coherence tomography (OCT) in two cases treated with DCB angioplasty.</div></div>","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"76 ","pages":"Pages 107-109"},"PeriodicalIF":1.9000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular Revascularization Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1553838925000636","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Drug-coated balloons (DCB) have evolved as an alternative to drug-eluting stents in coronary interventions without the addition of an extra metal layer while delivering antiproliferative drugs. However, the delivery of the drug at the target site cannot be objectively assessed in routine practice. Hence, the success of a DCB angioplasty is limited to luminal gain alone. We report a novel finding of tiny paclitaxel crystals detected on the intimal surface by intravascular ultrasound (IVUS) and optical coherence tomography (OCT) in two cases treated with DCB angioplasty.
期刊介绍：
Cardiovascular Revascularization Medicine (CRM) is an international and multidisciplinary journal that publishes original laboratory and clinical investigations related to revascularization therapies in cardiovascular medicine. Cardiovascular Revascularization Medicine publishes articles related to preclinical work and molecular interventions, including angiogenesis, cell therapy, pharmacological interventions, restenosis management, and prevention, including experiments conducted in human subjects, in laboratory animals, and in vitro. Specific areas of interest include percutaneous angioplasty in coronary and peripheral arteries, intervention in structural heart disease, cardiovascular surgery, etc.
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