Boosting the antibacterial potency of natural products through nanotechnologies.

IF 5.3 2区 医学 Q1 PHARMACOLOGY & PHARMACY International Journal of Pharmaceutics Pub Date : 2025-03-06 DOI:10.1016/j.ijpharm.2025.125437
Min Jiao, Weiwen Kong, Wenjuan Liu, Zirong Dong, Jinlong Yang, Zibo Wei, Xinrui Lu, Yuning Wei, Jie Zhuang
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引用次数: 0

Abstract

The advent of bacterial resistance has led to a notable challenge in effectively treating bacterial infections. This highlights the urgent need for the development of novel and effective drugs to combat bacterial infections. Medicinal plants, with their rich and diverse natural compounds, represent a valuable source for the discovery of novel antibacterial agents. Many of these natural compounds exhibit strong antibacterial functions, offering a promising direction for the development of antibacterial drugs. Furthermore, the application of nanotechnology in the development of antibacterial natural products has become a topic of considerable interest due to the advantages it offers, including the potential to enhance drug solubility. The efficacy of natural antibacterial agents is significantly enhanced through nanotechnology. This review offers a comprehensive overview of recent advances in the delivery of natural antibacterial compounds using a range of nanoformulation strategies.

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来源期刊
CiteScore
10.70
自引率
8.60%
发文量
951
审稿时长
72 days
期刊介绍: The International Journal of Pharmaceutics is the third most cited journal in the "Pharmacy & Pharmacology" category out of 366 journals, being the true home for pharmaceutical scientists concerned with the physical, chemical and biological properties of devices and delivery systems for drugs, vaccines and biologicals, including their design, manufacture and evaluation. This includes evaluation of the properties of drugs, excipients such as surfactants and polymers and novel materials. The journal has special sections on pharmaceutical nanotechnology and personalized medicines, and publishes research papers, reviews, commentaries and letters to the editor as well as special issues.
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