Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection.

IF 1.3 Q4 INFECTIOUS DISEASES Southern African Journal of Infectious Diseases Pub Date : 2025-02-11 eCollection Date: 2025-01-01 DOI:10.4102/sajid.v40i1.685
Yoliswa Z Chili, Menzi B Nkosi, Nicky-Louise Byrne, Moepeng J Maseko, Stephen N J Korsman, Gert U van Zyl
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Abstract

This case report details haemorrhagic cystitis in a 49-year-old female with chronic lymphocytic leukaemia (CLL), recurrent haematuria and detected BK polyomavirus (BKPyV) and adenovirus (HAdV) in urine. During chemotherapy cycles, quantitative polymerase chain reaction (PCR) assays found high HAdV load, similar to a HAdV-B2 genotype 78, a rare genotype that is closely related to HAdV-11.

Contribution: Viral interactions reveal immune system vulnerabilities.

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出血性膀胱炎的病因学:BK多瘤病毒和腺病毒检测。
本病例报告详细介绍了一名49岁女性慢性淋巴细胞白血病(CLL)的出血性膀胱炎,复发性血尿并在尿液中检测到BK多瘤病毒(BKPyV)和腺病毒(hav)。在化疗周期中,定量聚合酶链反应(PCR)检测发现高hav载量,类似于hav - b2基因型78,这是一种与hav -11密切相关的罕见基因型。贡献:病毒相互作用揭示了免疫系统的脆弱性。
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来源期刊
自引率
11.10%
发文量
50
审稿时长
52 weeks
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