{"title":"Cold is hot for slowing aging","authors":"Matteo Cerri","doi":"10.1038/s43587-025-00817-1","DOIUrl":null,"url":null,"abstract":"Hrvatin and colleagues explore the antiaging mechanisms of torpor, and separate the roles of metabolic rate and body temperature. The study demonstrates that hypothermia, and not hypometabolism, drives deceleration of epigenetic aging, which positions body temperature as a pivotal target in aging research.","PeriodicalId":94150,"journal":{"name":"Nature aging","volume":"5 3","pages":"344-345"},"PeriodicalIF":19.4000,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature aging","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43587-025-00817-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
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Abstract
Hrvatin and colleagues explore the antiaging mechanisms of torpor, and separate the roles of metabolic rate and body temperature. The study demonstrates that hypothermia, and not hypometabolism, drives deceleration of epigenetic aging, which positions body temperature as a pivotal target in aging research.
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