GLP-1 receptor agonists: new treatment frontiers

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Abstract

Given the early success of treating diabetes and obesity with glucagon-like peptide-1 receptor agonists (GLP-1RAs) and their neurobiological effects, interest is mounting in identifying new clinical applications and repurposing of these drugs for the treatment of neuropsychiatric conditions. A growing body of evidence points to the potential of GLP-1RA medications for the treatment of specific mental disorders, which will open the door for continued development and refinement of this class of drugs.

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GLP-1受体激动剂:新的治疗前沿
鉴于胰高血糖素样肽-1受体激动剂(GLP-1RAs)治疗糖尿病和肥胖症的早期成功及其神经生物学效应,人们越来越关注这些药物在神经精神疾病治疗中的新的临床应用和重新定位。越来越多的证据指向GLP-1RA药物治疗特定精神障碍的潜力,这将为这类药物的持续开发和改进打开大门。
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