"Will the Real Demyelinating Disorder Please Stand Up?": From the National Multiple Sclerosis Society Case Conference Proceedings.

IF 7.8 1区 医学 Q1 CLINICAL NEUROLOGY Neurology® Neuroimmunology & Neuroinflammation Pub Date : 2025-05-01 Epub Date: 2025-03-10 DOI:10.1212/NXI.0000000000200380
Aisha Elfasi, Myla D Goldman, Claire Riley, Scott S Zamvil, Scott Douglas Newsome
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引用次数: 0

Abstract

A 46-year-old man presented with progressive painful monocular vision loss and left leg paresthesias. Workup demonstrated multifocal demyelinating lesions and CSF-restricted oligoclonal bands. He was diagnosed with multiple sclerosis (MS), but follow-up testing was notable for positive myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG). We discuss implications and clinical considerations for MOG-IgG positivity in MS.

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来源期刊
CiteScore
15.60
自引率
2.30%
发文量
219
审稿时长
8 weeks
期刊介绍: Neurology Neuroimmunology & Neuroinflammation is an official journal of the American Academy of Neurology. Neurology: Neuroimmunology & Neuroinflammation will be the premier peer-reviewed journal in neuroimmunology and neuroinflammation. This journal publishes rigorously peer-reviewed open-access reports of original research and in-depth reviews of topics in neuroimmunology & neuroinflammation, affecting the full range of neurologic diseases including (but not limited to) Alzheimer's disease, Parkinson's disease, ALS, tauopathy, and stroke; multiple sclerosis and NMO; inflammatory peripheral nerve and muscle disease, Guillain-Barré and myasthenia gravis; nervous system infection; paraneoplastic syndromes, noninfectious encephalitides and other antibody-mediated disorders; and psychiatric and neurodevelopmental disorders. Clinical trials, instructive case reports, and small case series will also be featured.
期刊最新文献
Abnormal Brain MRI in Anti-NMDA Receptor Encephalitis: Clinical and Prognostic Implications. Evolution of Chronic Lesion Tissue in Relapsing-Remitting Patients With Multiple Sclerosis: An Association With Disease Progression. HLA Association With AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder in the Korean Population. Single-Cell RNA Sequencing in Incontinentia Pigmenti With Neonatal Encephalopathy Reveals Broad Immune Activation Moderated by Steroids. "Will the Real Demyelinating Disorder Please Stand Up?": From the National Multiple Sclerosis Society Case Conference Proceedings.
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