Radiomics for differential diagnosis of ischemic and dilated cardiomyopathy using non-contrast-enhanced cine cardiac magnetic resonance imaging.

IF 9.7 1区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Radiologia Medica Pub Date : 2025-03-10 DOI:10.1007/s11547-025-01979-z
Jaravee Lasode, Warath Chantaksinopas, Sararas Khongwirotphan, Pairoj Chattranukulchai, Yongkasem Vorasettakarnkij, Sira Sriswasdi, Monravee Tumkosit, Yothin Rakvongthai
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引用次数: 0

Abstract

Objective: Our study investigated the effectiveness of using radiomics and non-gadolinium cine cardiac magnetic resonance (CMR) imaging for differential diagnosis between ischemic and dilated cardiomyopathy (ICM vs. DCM) and detecting myocardial scar without relying on gadolinium-based contrast agents.

Materials and methods: We retrospectively enrolled 200 patients with age 18 who were diagnosed with ICM and DCM, both with and without myocardial scars, and had complete short-axis cine CMR images without artifacts over the heart area. Radiomic features were extracted from the myocardium and blood pools in short-axis cine CMR images. Feature selection was performed using intraclass correlation coefficient and recursive feature elimination with cross-validation (RFECV). Multivariate analysis with logistic regression was utilized to construct 3 radiomic models (ICM vs DCM, Scar vs NoScar in ICM and in DCM). Model performance was evaluated using area under the receiver operating characteristic (ROC) curve (AUC) and compared with radiologist's performance using cine CMR images.

Results: For each of the three models, 21, 14, and 19 radiomic features were selected. The AUC values of each model were 0.964 ± 0.008, 0.989 ± 0.004, and 0.996 ± 0.004, respectively, in the training set and 0.918 ± 0.040, 0.955 ± 0.045, and 0.935 ± 0.052, respectively, in the test set (p < 0.0001). The radiomic models outperformed the radiologist as shown by the ROC curve.

Conclusions: Radiomics showed promise in differentiating between ICM and DCM and detecting myocardial scar with cine CMR images, which offered an alternative for ICM and DCM differentiation in patients with gadolinium contraindication.

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来源期刊
Radiologia Medica
Radiologia Medica 医学-核医学
CiteScore
14.10
自引率
7.90%
发文量
133
审稿时长
4-8 weeks
期刊介绍: Felice Perussia founded La radiologia medica in 1914. It is a peer-reviewed journal and serves as the official journal of the Italian Society of Medical and Interventional Radiology (SIRM). The primary purpose of the journal is to disseminate information related to Radiology, especially advancements in diagnostic imaging and related disciplines. La radiologia medica welcomes original research on both fundamental and clinical aspects of modern radiology, with a particular focus on diagnostic and interventional imaging techniques. It also covers topics such as radiotherapy, nuclear medicine, radiobiology, health physics, and artificial intelligence in the context of clinical implications. The journal includes various types of contributions such as original articles, review articles, editorials, short reports, and letters to the editor. With an esteemed Editorial Board and a selection of insightful reports, the journal is an indispensable resource for radiologists and professionals in related fields. Ultimately, La radiologia medica aims to serve as a platform for international collaboration and knowledge sharing within the radiological community.
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