{"title":"Analysis of clinical efficacy of sacral magnetic stimulation for the treatment of detrusor underactivity.","authors":"Huixian Pan, Chenhao Tang, Chen Song, Junhua Li","doi":"10.3389/fneur.2025.1499310","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to investigate the effectiveness and safety of sacral magnetic stimulation (SMS) in the management of detrusor underactivity (DU).</p><p><strong>Methods: </strong>We retrospectively analyzed 66 patients with detrusor underactivity treated at Hangzhou Third People's Hospital from January 2020 to October 2024, divided into two groups (33 cases each). Both groups had confirmed detrusor underactivity via urodynamic studies. The control group received conventional treatment (medication, catheterization, bladder training), while the observation group received SMS therapy. Urination diaries, urodynamic parameters and self-rating anxiety scale (SAS) were collected before and after the 4-week treatment to evaluate SMS efficacy and safety.</p><p><strong>Results: </strong>All patients in the observation group completed the course of sacral magnetic stimulation without experiencing any serious complications. After treatment, the observation group showed a significant reduction in the number of daily urinations, nocturnal urinations, SAS score and residual urine volume (RUV) (<i>p</i> < 0.05) compared with the control group. There was no statistically significant difference in maximum cystometric capacity (MCC) (<i>p</i> > 0.05). However, improvements were observed in SAS score, Detrusor Pressure at Maximum Flow (Pdet), Bladder Contractility Index (BCI), Maximum urinary Flow Rate (Qmax) and Average Urinary Flow Rate (Qavg) (<i>p</i> < 0.05). The effective rate in the observation group was 78.78%, significantly higher than that in the control group (<i>p</i> < 0.05). Although there was a slight decrease in the effective rate during the 6-month follow-up, the difference was not statistically significant (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>In conclusion, sacral magnetic stimulation therapy has demonstrated effectiveness in improving urinary function in patients with detrusor underactivity while maintaining a high level of safety.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1499310"},"PeriodicalIF":2.8000,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893392/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Neurology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fneur.2025.1499310","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: The objective of this study was to investigate the effectiveness and safety of sacral magnetic stimulation (SMS) in the management of detrusor underactivity (DU).
Methods: We retrospectively analyzed 66 patients with detrusor underactivity treated at Hangzhou Third People's Hospital from January 2020 to October 2024, divided into two groups (33 cases each). Both groups had confirmed detrusor underactivity via urodynamic studies. The control group received conventional treatment (medication, catheterization, bladder training), while the observation group received SMS therapy. Urination diaries, urodynamic parameters and self-rating anxiety scale (SAS) were collected before and after the 4-week treatment to evaluate SMS efficacy and safety.
Results: All patients in the observation group completed the course of sacral magnetic stimulation without experiencing any serious complications. After treatment, the observation group showed a significant reduction in the number of daily urinations, nocturnal urinations, SAS score and residual urine volume (RUV) (p < 0.05) compared with the control group. There was no statistically significant difference in maximum cystometric capacity (MCC) (p > 0.05). However, improvements were observed in SAS score, Detrusor Pressure at Maximum Flow (Pdet), Bladder Contractility Index (BCI), Maximum urinary Flow Rate (Qmax) and Average Urinary Flow Rate (Qavg) (p < 0.05). The effective rate in the observation group was 78.78%, significantly higher than that in the control group (p < 0.05). Although there was a slight decrease in the effective rate during the 6-month follow-up, the difference was not statistically significant (p > 0.05).
Conclusion: In conclusion, sacral magnetic stimulation therapy has demonstrated effectiveness in improving urinary function in patients with detrusor underactivity while maintaining a high level of safety.
目的:探讨骶骨磁刺激(SMS)治疗逼尿肌活动不足(DU)的有效性和安全性。方法:回顾性分析杭州市第三人民医院2020年1月至2024年10月收治的66例逼尿肌活动不足患者,分为两组,每组33例。两组均通过尿动力学研究证实逼尿肌活动不足。对照组采用常规治疗(药物、导尿、膀胱训练),观察组采用SMS治疗。在治疗4周前后收集排尿日记、尿动力学参数和焦虑自评量表(SAS),评价SMS的疗效和安全性。结果:观察组患者均完成骶骨磁刺激疗程,无严重并发症发生。治疗后观察组患者日排尿次数、夜排尿次数、SAS评分、剩余尿量(RUV)均显著降低(p p > 0.05)。但SAS评分、最大尿流逼尿肌压力(Pdet)、膀胱收缩指数(BCI)、最大尿流率(Qmax)和平均尿流率(Qavg) (p p p > 0.05)均有改善。结论:综上所述,骶椎磁刺激治疗在保持高安全性的同时,可以有效改善逼尿肌活动不足患者的泌尿功能。
期刊介绍:
The section Stroke aims to quickly and accurately publish important experimental, translational and clinical studies, and reviews that contribute to the knowledge of stroke, its causes, manifestations, diagnosis, and management.