{"title":"Exposure to ambient air pollution increases risk","authors":"Annette Fenner","doi":"10.1038/s41585-025-01021-x","DOIUrl":null,"url":null,"abstract":"<p>Air pollution has been suggested as a potential modifiable risk factor for prostate cancer, but data remain inconsistent. Now a study of over 210,000 men from a UK biobank suggests that long-term exposure to air pollution increases prostate cancer risk.</p><p>Data from 210,722 men who were free of prostate cancer at baseline were collected from the UK Biobank. The mean age of these men was 56.6 years, and 10,841 men were diagnosed with incident prostate cancer during a total of 2,228,981 person-years of follow-up monitoring (median follow-up duration 10.9 years). This information was cross-referenced with air pollution data from the UK government Department for Environment, Food & Rural Affairs, which included ambient air pollutants, such as particulate matter with diameters ≤2.5 μm (PM<sub>2.5</sub>) and ≤10 μm (PM<sub>10</sub>), nitrogen oxides (NO<sub>2</sub> and NO<sub><i>x</i></sub>), sulfur dioxide (SO<sub>2</sub>), benzene and ozone (O<sub>3</sub>).</p>","PeriodicalId":19088,"journal":{"name":"Nature Reviews Urology","volume":"56 1","pages":""},"PeriodicalIF":12.1000,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41585-025-01021-x","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Air pollution has been suggested as a potential modifiable risk factor for prostate cancer, but data remain inconsistent. Now a study of over 210,000 men from a UK biobank suggests that long-term exposure to air pollution increases prostate cancer risk.
Data from 210,722 men who were free of prostate cancer at baseline were collected from the UK Biobank. The mean age of these men was 56.6 years, and 10,841 men were diagnosed with incident prostate cancer during a total of 2,228,981 person-years of follow-up monitoring (median follow-up duration 10.9 years). This information was cross-referenced with air pollution data from the UK government Department for Environment, Food & Rural Affairs, which included ambient air pollutants, such as particulate matter with diameters ≤2.5 μm (PM2.5) and ≤10 μm (PM10), nitrogen oxides (NO2 and NOx), sulfur dioxide (SO2), benzene and ozone (O3).
期刊介绍：
Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline.
The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals.
Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.
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