A Low-Cost Optomechatronic Diffuse Optical Mammography System for 3D Image Reconstruction: Proof of Concept.

IF 3.3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Diagnostics Pub Date : 2025-02-27 DOI:10.3390/diagnostics15050584
Josué D Rivera-Fernández, Alfredo Hernández-Mendoza, Diego A Fabila-Bustos, José M de la Rosa-Vázquez, Macaria Hernández-Chávez, Gabriela de la Rosa-Gutierrez, Karen Roa-Tort
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Abstract

Background: The development and initial testing of an optomechatronic system for the reconstruction of three-dimensional (3D) images to identify abnormalities in breast tissue and assist in the diagnosis of breast cancer is presented. Methods: This system combines 3D reconstruction technology with diffuse optical mammography (DOM) to offer a detecting tool that complements and assists medical diagnosis. DOM analyzes tissue properties with light, detecting density and composition variations. Integrating 3D reconstruction enables detailed visualization for precise tumor localization and sizing, offering more information than traditional methods. This technological combination enables more accurate, earlier diagnoses and helps plan effective treatments by understanding the patient's anatomy and tumor location. Results: Using Chinese ink, it was possible to identify simulated abnormalities of 10, 15, and 20 mm in diameter in breast tissue phantoms from cosmetic surgery. Conclusions: Data can be processed using algorithms to generate three-dimensional images, providing a non-invasive and safe approach for detecting anomalies. Currently, the system is in a pilot testing phase using breast tissue phantoms, enabling the evaluation of its accuracy and functionality before application in clinical studies.

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用于3D图像重建的低成本光机电漫射光学乳房x线照相术系统:概念验证。
背景:本文介绍了一种用于重建三维(3D)图像的光机电系统的开发和初步测试,以识别乳腺组织中的异常并协助诊断乳腺癌。方法:该系统将三维重建技术与漫射光学乳房x线摄影(DOM)相结合,提供一种补充和辅助医学诊断的检测工具。DOM利用光线分析组织特性,检测密度和成分变化。集成3D重建可以实现精确肿瘤定位和大小的详细可视化,提供比传统方法更多的信息。这种技术的结合可以更准确、更早地诊断,并通过了解患者的解剖结构和肿瘤位置,帮助制定有效的治疗方案。结果:使用中国墨水,可以识别直径为10、15和20 mm的乳房组织幻象。结论:数据可以通过算法处理生成三维图像,为异常检测提供了一种无创、安全的方法。目前,该系统正处于使用乳腺组织模型的试点测试阶段,以便在应用于临床研究之前评估其准确性和功能。
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来源期刊
Diagnostics
Diagnostics Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
4.70
自引率
8.30%
发文量
2699
审稿时长
19.64 days
期刊介绍: Diagnostics (ISSN 2075-4418) is an international scholarly open access journal on medical diagnostics. It publishes original research articles, reviews, communications and short notes on the research and development of medical diagnostics. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodological details must be provided for research articles.
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