Initial demonstration of the Scratch-PET concept: an intraoperative PET with a hand-held detector.

IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Radiological Physics and Technology Pub Date : 2025-03-12 DOI:10.1007/s12194-025-00889-z
Taiyo Ishikawa, Yuma Iwao, Go Akamatsu, Sodai Takyu, Hideaki Tashima, Takayuki Okamoto, Taiga Yamaya, Hideaki Haneishi
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引用次数: 0

Abstract

Positron emission tomography (PET) is a valuable tool for diagnosing malignant tumors. Intraoperative PET imaging is expected to allow the more accurate localization of tumors that need resections. However, conventional devices feature a large detector ring that obstructs surgical procedures, preventing their intraoperative application. This paper proposes a new PET device, Scratch-PET, for image-guided tumor resection. The key feature of Scratch-PET is its use of a hand-held detector to scan the surgical field, ensuring open space for surgery while measuring annihilation radiation with a fixed detector array placed below the patient. We developed a prototype device using two detectors: the hand-held detector and a fixed detector, to demonstrate the feasibility of the proposed concept. Both detectors consisted of 16 × 16 arrays of lutetium yttrium orthosilicates (3 × 3 × 15 mm3) coupled one-to-one with 16 × 16 silicon photomultiplier arrays. The position and orientation of the hand-held detector are tracked using an optical tracking sensor that detects attached markers. We measured a 22Na multi-rod phantom and two 22Na point sources separately for 180 s while moving the hand-held detector. The rod diameters were 6.0, 5.0, 4.0, 3.0, 2.2, and 1.6 mm. Each point source was placed at the field-of-view center and 35 mm off-center which was outside the sensitive area when the hand-held detector was positioned facing the fixed detector. The 2.2 mm rods were partially resolved, and both point sources were successfully visualized. The potential of the proposed device to visualize small tumors was validated.

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来源期刊
Radiological Physics and Technology
Radiological Physics and Technology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
3.00
自引率
12.50%
发文量
40
期刊介绍: The purpose of the journal Radiological Physics and Technology is to provide a forum for sharing new knowledge related to research and development in radiological science and technology, including medical physics and radiological technology in diagnostic radiology, nuclear medicine, and radiation therapy among many other radiological disciplines, as well as to contribute to progress and improvement in medical practice and patient health care.
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