{"title":"Prediction of Myocardial Infarction Based on Non-ECG Sleep Data Combined With Domain Knowledge","authors":"Changyun Li;Yonghan Zhao;Qihui Mo;Zhibing Wang;Xi Xu","doi":"10.1109/ACCESS.2025.3548118","DOIUrl":null,"url":null,"abstract":"Prediction of myocardial infarction (MI) is crucial for early intervention and treatment. Machine learning has increasingly been applied in the realm of disease prediction. This study explores the feasibility of utilizing easily obtainable heart rate (HR) and respiratory rate (RR) data collected during nocturnal sleep, in conjunction with clinical characteristics and medical domain knowledge, to predict MI. Data for this investigation were sourced from the Sleep Heart Health Study (SHHS) program in the United States, which was categorized into MI and non-MI groups based on the occurrence or absence of MI during follow-up, involving a total of 488 participants. Multiple features related to HR and RR were extracted and integrated with clinical features; four algorithms—MLP, SVM, XGBoost, and CNN—were employed for model construction. The findings indicated that the MLP model exhibited superior performance, achieving an accuracy rate 71.1%. Furthermore, three medical rules age, HR, and RR were incorporated into the MLP model to mitigate the limitations of small sample sizes. The experiments demonstrate that the model’s accuracy reaches its optimal level by combining the age rule, improving to 73.1%. The findings indicate that leveraging non-cardiac electrophysiological data obtained during sleep alongside medical domain knowledge can significantly enhance the accuracy of early predictions regarding cardiac MI while offering novel insights for its prevention and diagnosis.","PeriodicalId":13079,"journal":{"name":"IEEE Access","volume":"13 ","pages":"42262-42271"},"PeriodicalIF":3.4000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10910191","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Access","FirstCategoryId":"94","ListUrlMain":"https://ieeexplore.ieee.org/document/10910191/","RegionNum":3,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"COMPUTER SCIENCE, INFORMATION SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Prediction of myocardial infarction (MI) is crucial for early intervention and treatment. Machine learning has increasingly been applied in the realm of disease prediction. This study explores the feasibility of utilizing easily obtainable heart rate (HR) and respiratory rate (RR) data collected during nocturnal sleep, in conjunction with clinical characteristics and medical domain knowledge, to predict MI. Data for this investigation were sourced from the Sleep Heart Health Study (SHHS) program in the United States, which was categorized into MI and non-MI groups based on the occurrence or absence of MI during follow-up, involving a total of 488 participants. Multiple features related to HR and RR were extracted and integrated with clinical features; four algorithms—MLP, SVM, XGBoost, and CNN—were employed for model construction. The findings indicated that the MLP model exhibited superior performance, achieving an accuracy rate 71.1%. Furthermore, three medical rules age, HR, and RR were incorporated into the MLP model to mitigate the limitations of small sample sizes. The experiments demonstrate that the model’s accuracy reaches its optimal level by combining the age rule, improving to 73.1%. The findings indicate that leveraging non-cardiac electrophysiological data obtained during sleep alongside medical domain knowledge can significantly enhance the accuracy of early predictions regarding cardiac MI while offering novel insights for its prevention and diagnosis.
IEEE AccessCOMPUTER SCIENCE, INFORMATION SYSTEMSENGIN-ENGINEERING, ELECTRICAL & ELECTRONIC
CiteScore
9.80
自引率
7.70%
发文量
6673
审稿时长
6 weeks
期刊介绍:
IEEE Access® is a multidisciplinary, open access (OA), applications-oriented, all-electronic archival journal that continuously presents the results of original research or development across all of IEEE''s fields of interest.
IEEE Access will publish articles that are of high interest to readers, original, technically correct, and clearly presented. Supported by author publication charges (APC), its hallmarks are a rapid peer review and publication process with open access to all readers. Unlike IEEE''s traditional Transactions or Journals, reviews are "binary", in that reviewers will either Accept or Reject an article in the form it is submitted in order to achieve rapid turnaround. Especially encouraged are submissions on:
Multidisciplinary topics, or applications-oriented articles and negative results that do not fit within the scope of IEEE''s traditional journals.
Practical articles discussing new experiments or measurement techniques, interesting solutions to engineering.
Development of new or improved fabrication or manufacturing techniques.
Reviews or survey articles of new or evolving fields oriented to assist others in understanding the new area.