{"title":"Nobel Prize for the discovery of microRNA and its role in gene regulation","authors":"Krisztina Hagymási","doi":"10.1007/s11224-025-02462-1","DOIUrl":null,"url":null,"abstract":"<div><p>The Nobel Prize 2024 in Physiology or Medicine has been awarded for the discovery of miRNA and its role in post-transcriptional gene regulation. Firstly, the results were thought to be irrelevant to humans, but nowadays, at least 30% of the known miRNAs could be used as novel biomarkers for screening human diseases and therapeutic purposes targeting manipulation of cell functions under examinations.</p></div>","PeriodicalId":780,"journal":{"name":"Structural Chemistry","volume":"36 2","pages":"759 - 765"},"PeriodicalIF":2.2000,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Structural Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s11224-025-02462-1","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The Nobel Prize 2024 in Physiology or Medicine has been awarded for the discovery of miRNA and its role in post-transcriptional gene regulation. Firstly, the results were thought to be irrelevant to humans, but nowadays, at least 30% of the known miRNAs could be used as novel biomarkers for screening human diseases and therapeutic purposes targeting manipulation of cell functions under examinations.
期刊介绍：
Structural Chemistry is an international forum for the publication of peer-reviewed original research papers that cover the condensed and gaseous states of matter and involve numerous techniques for the determination of structure and energetics, their results, and the conclusions derived from these studies. The journal overcomes the unnatural separation in the current literature among the areas of structure determination, energetics, and applications, as well as builds a bridge to other chemical disciplines. Ist comprehensive coverage encompasses broad discussion of results, observation of relationships among various properties, and the description and application of structure and energy information in all domains of chemistry.
We welcome the broadest range of accounts of research in structural chemistry involving the discussion of methodologies and structures,experimental, theoretical, and computational, and their combinations. We encourage discussions of structural information collected for their chemicaland biological significance.
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