Anatomical variations and their association with carpal tunnel syndrome: a comparison with healthy controls.

IF 2.6 3区医学 Q2 ORTHOPEDICS International Orthopaedics Pub Date : 2025-04-01 Epub Date: 2025-03-13 DOI:10.1007/s00264-025-06480-w

Michaela Gruber, Agnes Wawrik, Florin Gasser, Barbara Ebner, Philipp Reitbauer, Robert Uzel, Rodolphe Poupardin, Maximilian Mahrhofer, Laurenz Weitgasser, Karl Schwaiger, Gottfried Schaffler, Gottfried Wechselberger, Elisabeth Russe

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Abstract

Purpose: The prevalence of carpal tunnel syndrome (CTS) as the foremost upper extremity entrapment neuropathy is well-documented. The present study aimed to evaluate the prevalence of anatomical variations in the carpal tunnel and their potential role as risk factors for CTS.

Methods: Data from 447 CTS patients who underwent median nerve decompression between 2018 and 2019 were retrospectively analyzed. As a control group, 200 hands from 103 age- and sex-matched asymptomatic volunteers were further investigated.

Results: Anatomical variations identified through ultrasound in 19.7% of CTS hands and 16.0% of controls. Specifically, 10.3% of CTS hands had persistent median arteries, while 14.3% had bifid median nerves. Both variations occurred in 4.9% of CTS patients. In the control group, 13.0% had persistent median arteries and 11.0% had bifid median nerves, with both found in 8.0%.

Conclusions: Anatomical variations were found in both, CTS patients and controls, but their prevalence did not differ significantly between groups, suggesting they are not independent risk factors for CTS.

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解剖变异及其与腕管综合征的关系：与健康对照的比较

目的：腕管综合征（carpal tunnel syndrome， CTS）作为上肢压迫性神经病变的发病率是有充分文献记载的。本研究旨在评估腕管解剖变异的普遍性及其作为CTS危险因素的潜在作用。方法：回顾性分析2018年至2019年接受正中神经减压术的447例CTS患者的数据。作为对照组，来自103名年龄和性别匹配的无症状志愿者的200只手被进一步调查。结果：CTS组19.7%的手和对照组16.0%的手通过超声发现解剖变异。具体来说，10.3%的CTS手有持续的正中动脉，14.3%有两裂正中神经。4.9%的CTS患者出现了这两种变异。在对照组中，13.0%存在持续性正中动脉，11.0%存在双裂正中神经，两者均为8.0%。结论：CTS患者和对照组均存在解剖变异，但其患病率在组间无显著差异，提示其不是CTS的独立危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Orthopaedics 医学-整形外科

CiteScore

5.50

自引率

7.40%

发文量

360

审稿时长

1 months

期刊介绍： International Orthopaedics, the Official Journal of the Société Internationale de Chirurgie Orthopédique et de Traumatologie (SICOT) , publishes original papers from all over the world. The articles deal with clinical orthopaedic surgery or basic research directly connected with orthopaedic surgery. International Orthopaedics will also link all the members of SICOT by means of an insert that will be concerned with SICOT matters. Finally, it is expected that news and information regarding all aspects of orthopaedic surgery, including meetings, panels, instructional courses, etc. will be brought to the attention of the readers. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been approved by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted. Reports of animal experiments must state that the "Principles of laboratory animal care" (NIH publication No. 85-23, revised 1985) were followed, as well as specific national laws (e.g. the current version of the German Law on the Protection of Animals) where applicable. The editors reserve the right to reject manuscripts that do not comply with the above-mentioned requirements. The author will be held responsible for false statements or for failure to fulfil the above-mentioned requirements.