Greek Consensus on Chronic Lymphocytic Leukemia (CLL) Treatment.

IF 1.5 4区 医学 Q3 HEMATOLOGY Mediterranean Journal of Hematology and Infectious Diseases Pub Date : 2025-03-01 eCollection Date: 2025-01-01 DOI:10.4084/MJHID.2025.014
Sotirios Sachanas, Theodoros Vassilakopoulos, Maria Angelopoulou, Sotirios Papageorgiou, Emmanouil Spanoudakis, Maria Bouzani, Maria Dimou, Panagiotis Panagiotidis
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Abstract

Background: New targeted therapies have revolutionized the treatment landscape in CLL. Biological features, patient characteristics and preferences and the safety profile of each treatment option should be taken into consideration for making the optimal treatment choice. This consensus practice statement on CLL treatment was developed by a group of Greek experts in CLL based on the available evidence for both first-line treatment and the relapsed/refractory setting.

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希腊慢性淋巴细胞白血病 (CLL) 治疗共识。
背景:新的靶向治疗已经彻底改变了CLL的治疗前景。在做出最佳治疗选择时,应考虑生物学特征、患者特征和偏好以及每种治疗方案的安全性。CLL治疗的共识实践声明是由一组希腊CLL专家根据一线治疗和复发/难治性环境的现有证据制定的。
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来源期刊
CiteScore
4.20
自引率
6.20%
发文量
113
审稿时长
12 weeks
期刊介绍: Reciprocal interdependence between infectious and hematologic diseases (malignant and non-malignant) is well known. This relationship is particularly evident in Mediterranean countries. Parasitosis as Malaria, Leishmaniosis, B Hookworms, Teniasis, very common in the southeast Mediterranean area, infect about a billion people and manifest prevalently with anemia so that they are usually diagnosed mostly by experienced hematologist on blood or bone marrow smear. On the other hand, infections are also a significant problem in patients affected by hematological malignancies. The blood is the primary vector of HIV infection, which otherwise manifest with symptoms related to a reduction in T lymphocytes. In turn, infections can favor the insurgency of hematological malignancies. The causative relationship between Epstein-Barr virus infection, Helicobacter pylori, hepatitis C virus, HIV and lymphoproliferative diseases is well known.
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