Pleuroparenchymal Fibroelastosis: Update on CT and Histologic Findings.

IF 3.8 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Radiology. Cardiothoracic imaging Pub Date : 2025-04-01 DOI:10.1148/ryct.240382
Joel L Gamble, Nestor L Müller, Andrew Churg, Ana-Maria Bilawich
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Abstract

Pleuroparenchymal fibroelastosis (PPFE) is an interstitial lung disease (ILD) characterized at CT by upper lobe-predominant pleural thickening and subpleural fibrosis and histologically by visceral pleural fibrosis and subpleural fibroelastosis. Although initially classified as a rare idiopathic interstitial pneumonia, many cases are related to known risk factors, particularly hematopoietic stem cell and lung transplant, or observed in association with other ILDs. This review summarizes the diagnostic criteria for PPFE and illustrates the CT and histologic manifestations, aiming to familiarize the radiologist with the range of findings suggestive of the diagnosis. Keywords: Conventional Radiography, CT, Pulmonary, Thorax, Lung, Pleura, Complications, Transplantation, Fibrosis © RSNA, 2025.

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Incremental Prognostic Value of Perivascular Fat Attenuation Index in Patients with Diabetes with Coronary Artery Disease. Multimodality Imaging for the Diagnosis and Evaluation of Pulmonary Sarcoidosis. Coronary Artery Calcium Detection with Dual-Energy Posteroanterior and Lateral Chest Radiography: Imaging Clues and Added Value of the Lateral View. Denoised Ultra-Low-Dose Chest CT to Assess Pneumonia in Individuals Who Are Immunocompromised. Pleuroparenchymal Fibroelastosis: Update on CT and Histologic Findings.
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