Bang Du, Shuxin Liang, Rui Zhang, Wenjia Shi, Ruonan Wang, Yahong Qin, Aiai Chu
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引用次数: 0
Abstract
Background
Right ventricular (RV) diastolic function and right atrial (RA) function are poorly characterized in patients with obstructive sleep apnea syndrome (OSAS), but may influence exercise capacity. We aimed to evaluate RA function and RV diastolic function in OSAS and study their relationship with exercise capacity.
Methods
Fifty-three patients with OSAS and thirty age- and gender-matched controls prospectively underwent echocardiography and cardiopulmonary exercise testing to investigate RV diastolic function, RA function, and exercise capacity.
Results
Altered RV diastolic function in patients with severe OSAS was indicated by the increased tricuspid valve E/e′ ratio (TV E/e′), isovolumic relaxation time (IVRT), and by the reduced RV TDI e′ velocity. The TV E/e′ correlated modestly with peak VO2 (r = −0.334, p < 0.01). Patients with severe OSAS exhibited impaired RA total emptying fraction, RA passive emptying fraction, and RA reservoir strain (RARS), with RARS being associated with peak oxygen uptake (VO2) (r = 0.451, p < 0.01 for reservoir function).
Conclusion
Altered RA function and RV diastolic function in patients with OSAS are associated with impaired exercise capacity. The correlation of RA function and RV diastolic function with exercise capacity suggests that it may be important to evaluate RA function and RV diastolic function in this population.
期刊介绍:
Echocardiography: A Journal of Cardiovascular Ultrasound and Allied Techniques is the official publication of the International Society of Cardiovascular Ultrasound. Widely recognized for its comprehensive peer-reviewed articles, case studies, original research, and reviews by international authors. Echocardiography keeps its readership of echocardiographers, ultrasound specialists, and cardiologists well informed of the latest developments in the field.