Acute intestinal obstruction due to duodenal metastasis of laryngeal squamous cell carcinoma: A CARE case report.

IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-13 DOI:10.1016/j.anorl.2025.02.004
Y Lelonge, A Havasi, N Williet, B Le Roy
{"title":"Acute intestinal obstruction due to duodenal metastasis of laryngeal squamous cell carcinoma: A CARE case report.","authors":"Y Lelonge, A Havasi, N Williet, B Le Roy","doi":"10.1016/j.anorl.2025.02.004","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To report a case of duodenal metastasis of laryngeal squamous cell carcinoma revealed by acute intestinal obstruction.</p><p><strong>Case report: </strong>A 55-year-old male was initially treated for cT4N1M0 laryngeal squamous cell carcinoma, with total laryngectomy, bilateral neck dissection, total thyroidectomy and pectoralis major flap. Subsequently, he received radiotherapy and chemotherapy. Then, he was periodically monitored, with clinical examination and cervicothoracic CT, according to guidelines. Three years later, he presented acute intestinal obstruction. Abdominal CT revealed a 35mm obstructive duodenal tumor involving the head of the pancreas. Gastroscopy enabled biopsies, which confirmed metastasis of the laryngeal carcinoma. After gastro-entero-anastomosis, a first line treatment with cisplatin, 5-fluorouracile and pembrozilumab was started. It was complicated by abdominal bleeding, which required inferior duodenopancreatic artery embolization and colic perforation requiring colectomy. Due to deterioration in general health, 2 injections of pembrozilumab alone were made. Then, because of progression, the patient received 1 second-line injection of docetaxel. He finally died of acute pancreatitis, 7 months after diagnosis.</p><p><strong>Conclusion: </strong>Duodenal metastasis of squamous cell carcinoma of the larynx is rare but possible. This case report highlights the importance of clinical and radiological monitoring, particularly in locally advanced tumor.</p>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Annals of Otorhinolaryngology-Head and Neck Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.anorl.2025.02.004","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Objective: To report a case of duodenal metastasis of laryngeal squamous cell carcinoma revealed by acute intestinal obstruction.

Case report: A 55-year-old male was initially treated for cT4N1M0 laryngeal squamous cell carcinoma, with total laryngectomy, bilateral neck dissection, total thyroidectomy and pectoralis major flap. Subsequently, he received radiotherapy and chemotherapy. Then, he was periodically monitored, with clinical examination and cervicothoracic CT, according to guidelines. Three years later, he presented acute intestinal obstruction. Abdominal CT revealed a 35mm obstructive duodenal tumor involving the head of the pancreas. Gastroscopy enabled biopsies, which confirmed metastasis of the laryngeal carcinoma. After gastro-entero-anastomosis, a first line treatment with cisplatin, 5-fluorouracile and pembrozilumab was started. It was complicated by abdominal bleeding, which required inferior duodenopancreatic artery embolization and colic perforation requiring colectomy. Due to deterioration in general health, 2 injections of pembrozilumab alone were made. Then, because of progression, the patient received 1 second-line injection of docetaxel. He finally died of acute pancreatitis, 7 months after diagnosis.

Conclusion: Duodenal metastasis of squamous cell carcinoma of the larynx is rare but possible. This case report highlights the importance of clinical and radiological monitoring, particularly in locally advanced tumor.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
目的:报告一例因急性肠梗阻而发现的喉鳞癌十二指肠转移病例:报告一例因急性肠梗阻而发现的喉鳞癌十二指肠转移病例:一名 55 岁男性最初因 cT4N1M0 喉鳞状细胞癌接受全喉切除术、双侧颈部切除术、全甲状腺切除术和胸大肌皮瓣术。随后,他接受了放疗和化疗。之后,他根据指南定期接受临床检查和颈胸部 CT 监测。三年后,他出现了急性肠梗阻。腹部 CT 发现了一个 35 毫米的十二指肠阻塞性肿瘤,肿瘤累及胰腺头部。胃镜活检证实了喉癌转移。胃肠吻合术后,患者开始接受顺铂、5-氟尿嘧啶和培美曲塞单抗的一线治疗。腹部出血使病情复杂化,需要进行十二指肠胰下动脉栓塞术,结肠穿孔需要进行结肠切除术。由于全身健康状况恶化,又单独注射了 2 次彭布罗齐单抗。随后,由于病情进展,患者接受了一次多西他赛二线注射。最终,他在确诊 7 个月后死于急性胰腺炎:结论:喉鳞癌的十二指肠转移虽然罕见,但却有可能发生。本病例报告强调了临床和放射学监测的重要性,尤其是对局部晚期肿瘤的监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
3.70
自引率
28.00%
发文量
97
审稿时长
12 days
期刊介绍: European Annals of Oto-rhino-laryngology, Head and Neck diseases heir of one of the oldest otorhinolaryngology journals in Europe is the official organ of the French Society of Otorhinolaryngology (SFORL) and the the International Francophone Society of Otorhinolaryngology (SIFORL). Today six annual issues provide original peer reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches and review articles giving most up-to-date insights in all areas of otology, laryngology rhinology, head and neck surgery. The European Annals also publish the SFORL guidelines and recommendations.The journal is a unique two-armed publication: the European Annals (ANORL) is an English language well referenced online journal (e-only) whereas the Annales Françaises d’ORL (AFORL), mail-order paper and online edition in French language are aimed at the French-speaking community. French language teams must submit their articles in French to the AFORL site. Federating journal in its field, the European Annals has an Editorial board of experts with international reputation that allow to make an important contribution to communication on new research data and clinical practice by publishing high-quality articles.
期刊最新文献
Acute intestinal obstruction due to duodenal metastasis of laryngeal squamous cell carcinoma: A CARE case report. Audiometry results in adult cochlear implant patients according to the electrode array. Contents Editorial Board Improving post-treatment follow-up of HPV-driven oropharyngeal cancers
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1