Preparation of Magnetite-Containing Composite Aerogels Based on the Alginate–Chitosan Complex

IF 1.4 4区 化学 Q4 PHYSICS, ATOMIC, MOLECULAR & CHEMICAL Russian Journal of Physical Chemistry B Pub Date : 2025-03-16 DOI:10.1134/S1990793124701707
N. A. Gorshkova, I. A. Palamarchuk, O. S. Brovko, A. A. Sloboda, A. D. Ivakhnov, A. V. Malkov, N. I. Bogdanovich, T. I. Lovdina
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Abstract

Composite aerogels were prepared from sodium alginate–chitosan binary hydrogels by including magnetite followed by drying in supercritical carbon dioxide. An optimum concentration of magnetite to be introduced in the sodium alginate–chitosan system and conditions for supercritical drying of the composite hydrogels in carbon dioxide were selected experimentally to obtain aerogel with a highly developed porous structure. The resulting aerogels were studied by low-temperature nitrogen adsorption and shown to have a developed mesoporous structure with open cylindrical pores, the maximum specific surface area being 300 m2/g. The experimental study showed that the developed magnetite-containing composite aerogels possess high bactericidal activity against S. aureus, E. coli, and B. subtilis. Due to this, they are very promising for creating various medical products based on them, including wound dressings, active drug carriers, and hemostatic or sorption materials.

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海藻酸盐-壳聚糖配合物制备含磁铁矿复合气凝胶
以海藻酸钠-壳聚糖二元水凝胶为原料,加入磁铁矿,在超临界二氧化碳中干燥,制备复合气凝胶。通过实验选择了海藻酸钠-壳聚糖体系中磁铁矿的最佳添加浓度和复合水凝胶在二氧化碳中超临界干燥的条件,得到了多孔结构高度发达的气凝胶。通过低温氮气吸附对所得气凝胶进行了研究,结果表明气凝胶具有发达的介孔结构,具有开放的圆柱形孔隙,最大比表面积为300 m2/g。实验研究表明,制备的含磁铁矿复合气凝胶对金黄色葡萄球菌、大肠杆菌和枯草芽孢杆菌具有较高的杀菌活性。因此,它们非常有希望以它们为基础制造各种医疗产品,包括伤口敷料、活性药物载体和止血或吸收材料。
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来源期刊
Russian Journal of Physical Chemistry B
Russian Journal of Physical Chemistry B 化学-物理:原子、分子和化学物理
CiteScore
2.20
自引率
71.40%
发文量
106
审稿时长
4-8 weeks
期刊介绍: Russian Journal of Physical Chemistry B: Focus on Physics is a journal that publishes studies in the following areas: elementary physical and chemical processes; structure of chemical compounds, reactivity, effect of external field and environment on chemical transformations; molecular dynamics and molecular organization; dynamics and kinetics of photoand radiation-induced processes; mechanism of chemical reactions in gas and condensed phases and at interfaces; chain and thermal processes of ignition, combustion and detonation in gases, two-phase and condensed systems; shock waves; new physical methods of examining chemical reactions; and biological processes in chemical physics.
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