Issue Cover (March 2025)

IF 1.9 3区 医学 Q2 ANATOMY & MORPHOLOGY Journal of Anatomy Pub Date : 2025-03-16 DOI:10.1111/joa.14245
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Abstract

Cover image: see F. Szabó et al., ‘Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long-term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets.’ By knocking out Snap25, they abolished regulated synaptic vesicle release from different subsets of deep-layer cortical pyramidal neurons, i.e., Rbp4-Cre+ (layer 5) or Drd1a-Cre+ (layer 6b, magenta) neurons, respectively. They examined the local and global effects on the development, density, and laminar distribution of GABAergic interneurons (parvalbumin, cyan) and the perineuronal nets (detected with Vicia villosa agglutinin, yellow).

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发行封面(2025年3月)
封面图片:见F. Szabó等人,“皮层第5层锥体神经元亚群的慢性沉默对小白蛋白中间神经元和神经元周围网的层流分布有长期影响。”通过敲除Snap25,他们分别消除了来自深层皮质锥体神经元不同亚群的受调节的突触囊泡释放,即Rbp4-Cre+(第5层)或Drd1a-Cre+(第6b层,洋红色)神经元。他们检查了局部和全局对gaba能中间神经元(小白蛋白,青色)和周围神经元网(用绒毛凝集素检测,黄色)的发育、密度和层状分布的影响。
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来源期刊
Journal of Anatomy
Journal of Anatomy 医学-解剖学与形态学
CiteScore
4.80
自引率
8.30%
发文量
183
审稿时长
4-8 weeks
期刊介绍: Journal of Anatomy is an international peer-reviewed journal sponsored by the Anatomical Society. The journal publishes original papers, invited review articles and book reviews. Its main focus is to understand anatomy through an analysis of structure, function, development and evolution. Priority will be given to studies of that clearly articulate their relevance to the anatomical community. Focal areas include: experimental studies, contributions based on molecular and cell biology and on the application of modern imaging techniques and papers with novel methods or synthetic perspective on an anatomical system. Studies that are essentially descriptive anatomy are appropriate only if they communicate clearly a broader functional or evolutionary significance. You must clearly state the broader implications of your work in the abstract. We particularly welcome submissions in the following areas: Cell biology and tissue architecture Comparative functional morphology Developmental biology Evolutionary developmental biology Evolutionary morphology Functional human anatomy Integrative vertebrate paleontology Methodological innovations in anatomical research Musculoskeletal system Neuroanatomy and neurodegeneration Significant advances in anatomical education.
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