Devansh Bajaj, Deepak Suvarna, H V Aradya, H P Nandeesh, Abhishek Kabra
{"title":"Sarcoidosis Presenting as Space Occupying Lesions in Liver.","authors":"Devansh Bajaj, Deepak Suvarna, H V Aradya, H P Nandeesh, Abhishek Kabra","doi":"10.4103/aam.aam_246_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>This case report illustrates a typical presentation of hepatic sarcoidosis, a granulomatous liver disease that often manifests as an extrapulmonary feature of systemic sarcoidosis. The patient, a 60-year-old female, exhibited dyspeptic symptoms and anorexia. An abdominal ultrasound revealed space-occupying lesions in the liver, and elevated levels of alkaline phosphatase and gamma-glutamyl transferase were noted. Liver biopsy findings showed Grade 2 macrovesicular steatosis and noncaseating granulomatous inflammation. In addition, significantly elevated angiotensin-converting enzyme levels were observed, further supporting the diagnosis. This case underscores the importance of recognizing hepatic granulomatous foci, which can be crucial in determining the etiology and facilitating the diagnosis of sarcoidosis. The combination of clinical, biochemical, and histological findings played a pivotal role in diagnosing systemic sarcoidosis with hepatic involvement.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of African Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/aam.aam_246_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: This case report illustrates a typical presentation of hepatic sarcoidosis, a granulomatous liver disease that often manifests as an extrapulmonary feature of systemic sarcoidosis. The patient, a 60-year-old female, exhibited dyspeptic symptoms and anorexia. An abdominal ultrasound revealed space-occupying lesions in the liver, and elevated levels of alkaline phosphatase and gamma-glutamyl transferase were noted. Liver biopsy findings showed Grade 2 macrovesicular steatosis and noncaseating granulomatous inflammation. In addition, significantly elevated angiotensin-converting enzyme levels were observed, further supporting the diagnosis. This case underscores the importance of recognizing hepatic granulomatous foci, which can be crucial in determining the etiology and facilitating the diagnosis of sarcoidosis. The combination of clinical, biochemical, and histological findings played a pivotal role in diagnosing systemic sarcoidosis with hepatic involvement.
期刊介绍：
The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
