Advancing surgical outcomes through cardiovascular biomarker sub-phenotyping

IF 9.2 1区 医学 Q1 ANESTHESIOLOGY British journal of anaesthesia Pub Date : 2025-03-14 DOI:10.1016/j.bja.2025.02.009
Bruno Garcia , Ashish K. Khanna , Matthieu Legrand
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Abstract

Recent findings from Gutierrez del Arroyo and colleagues identified distinct sub-phenotypes in patients undergoing major noncardiac surgery based on biomarkers such as N terminal pro-brain natriuretic peptide, renin, aldosterone, and angiotensin-converting enzyme 2, which were associated with varying risks of postoperative myocardial injury. Although their findings highlight the potential of sub-phenotyping for advancing perioperative precision medicine, further research is needed to validate these sub-phenotypes and explore their role in tailoring perioperative management strategies.
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通过心血管生物标志物亚表型提高手术效果。
Gutierrez del Arroyo及其同事最近的研究发现,在接受重大非心脏手术的患者中,基于生物标志物,如N端前脑利钠肽、肾素、醛固酮和血管紧张素转换酶2,确定了不同的亚表型,这些亚表型与术后心肌损伤的不同风险相关。尽管他们的研究结果强调了亚表型在推进围手术期精准医学方面的潜力,但需要进一步的研究来验证这些亚表型并探索它们在围手术期管理策略中的作用。
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来源期刊
CiteScore
13.50
自引率
7.10%
发文量
488
审稿时长
27 days
期刊介绍: The British Journal of Anaesthesia (BJA) is a prestigious publication that covers a wide range of topics in anaesthesia, critical care medicine, pain medicine, and perioperative medicine. It aims to disseminate high-impact original research, spanning fundamental, translational, and clinical sciences, as well as clinical practice, technology, education, and training. Additionally, the journal features review articles, notable case reports, correspondence, and special articles that appeal to a broader audience. The BJA is proudly associated with The Royal College of Anaesthetists, The College of Anaesthesiologists of Ireland, and The Hong Kong College of Anaesthesiologists. This partnership provides members of these esteemed institutions with access to not only the BJA but also its sister publication, BJA Education. It is essential to note that both journals maintain their editorial independence. Overall, the BJA offers a diverse and comprehensive platform for anaesthetists, critical care physicians, pain specialists, and perioperative medicine practitioners to contribute and stay updated with the latest advancements in their respective fields.
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