[Primary clinical, endoscopic and histologic findings in solitary rectal ulcer].

A Schneider, C Fritze, H Bosseckert, G Machnik
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Abstract

This study presents clinical, endoscopical and histological primary findings of solitary ulcer of the rectum obtained in 24 patients. Solitary ulcer of the rectum is preferably a disease of young women. The main symptom is recurrent rectal bleeding. Endoscopically in 50% of all cases mucosal ulcerations can be observed. The other cases are non-ulcerous lesions with uncharacteristic endoscopical findings. The majority of the lesions are within 6-8 cm of the anal margin. In 44% of the patients there are findings, which are suspicious of preexisting rectal prolapse. The histological main criterion is a fibromuscular hyperplasia of the lamina propria. Full agreement of endoscopical and histological diagnosis at primary examination could be obtained in only 17% of the cases.

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【孤立性直肠溃疡的主要临床、内镜和组织学表现】。
本研究报告了24例直肠孤立性溃疡的临床、内镜和组织学的初步表现。孤立性直肠溃疡多见于年轻女性。主要症状为复发性直肠出血。内镜下50%的病例可观察到粘膜溃疡。其他病例是非溃疡性病变,内窥镜检查结果不典型。大多数病变位于肛缘6- 8cm范围内。在44%的患者有发现,这是怀疑先前存在的直肠脱垂。组织学上的主要标准是固有层纤维性肌肉增生。只有17%的病例在初次检查时得到了内镜和组织学诊断的完全一致。
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