An Injection-Molded Modified Silicone Rubber for Cancer-on-Chip Applications (Adv. Mater. Technol. 6/2025)

IF 6.4 3区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Advanced Materials Technologies Pub Date : 2025-03-18 DOI:10.1002/admt.202570029
Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten
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Abstract

Cancer-on-Chip

In article number 2401450, Maayke M. P. Kuijten and co-workers present the culture of duo-layers with cancer cells on one and endothelial cells (to mimic a blood vessel) on the other. These cells have been cultured under continuous flow on an injection-molded functionalized PDMS fluidic insert for the Micronit® system and demonstrates the suitability of the inserts for building relevant cancer models on chip.

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一种用于芯片抗癌应用的注射成型改性硅橡胶。抛光工艺。6/2025)
在第2401450篇文章中,Maayke M. P. Kuijten和他的同事提出了一种双层细胞的培养方法,一层是癌细胞,另一层是内皮细胞(模拟血管)。这些细胞在microit®系统的注射成型功能化PDMS流体插入物上连续培养,并证明了插入物在芯片上构建相关癌症模型的适用性。
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来源期刊
Advanced Materials Technologies
Advanced Materials Technologies Materials Science-General Materials Science
CiteScore
10.20
自引率
4.40%
发文量
566
期刊介绍: Advanced Materials Technologies Advanced Materials Technologies is the new home for all technology-related materials applications research, with particular focus on advanced device design, fabrication and integration, as well as new technologies based on novel materials. It bridges the gap between fundamental laboratory research and industry.
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