The Impact of Timing of Percutaneous Coronary Intervention on the Prognosis of Non-ST Segment Elevation Myocardial Infarction Patients.

IF 0.9 4区医学 Q3 SURGERY Annali italiani di chirurgia Pub Date : 2025-01-01 DOI:10.62713/aic.3339

Tianzhu Li, Nimin Lu, Yingxue Dong

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Abstract

Aim: To study the effect of timing of percutaneous coronary intervention (PCI) to prognosis of Non-ST segment elevation myocardial infarction (NSTEMI) patients.

Methods: 295 Patients were derived from our hospital who were diagnosed as NSTEMI and accepted PCI therapy in 24 hours from admission during March 2017 to May 2020. According to results of coronary angiography, patients with NSTEMI were divided into culprit artery occlusion (CO, n = 117) and non-culprit artery occlusion (N-CO, n = 178) two groups and then according to timing of PCI into three categories: <6 h, 6-12 h and 12-24 h from admission. We defined major adverse cardiovascular events (MACE) in 1 year follow.

Results: In this study, with earlier time to PCI, the incidence of MACE was lower in NSTEMI patients with CO. The incidence of MACE was higher in the CO group than in the N-CO group (25.8% vs. 36.8%, p = 0.046). The incidence of MACE was 11.8% in T1 (<6 h) group (n = 50), less than 29.4% in T2 (6-12 h) group (n = 30) and 43.4% in T3 (12-24 h) group (n = 215), with a statistically significant difference (p = 0.044). However, this phenomenon does not occur in N-CO group. As the duration of PCI increased, patient survival decreased progressively over the course of follow-up in NSTEMI with CO (p = 0.048).

Conclusions: Our study found that early PCI improves the prognosis of NSTEMI patients with culprit artery occlusion.

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经皮冠状动脉介入治疗时机对非st段抬高型心肌梗死患者预后的影响。

目的：探讨经皮冠状动脉介入治疗（PCI）时机对非st段抬高型心肌梗死（NSTEMI）患者预后的影响。方法：选取我院2017年3月至2020年5月入院24小时内确诊为NSTEMI并接受PCI治疗的295例患者。根据冠状动脉造影结果，将NSTEMI患者分为元凶动脉闭塞（CO, n = 117）和非元凶动脉闭塞（n = 178）两组，再根据PCI时间分为三类：结果：本研究中，NSTEMI合并CO患者MACE发生率随PCI时间的提前而降低，CO组MACE发生率高于n- CO组（25.8% vs. 36.8%, p = 0.046）。结论：我们的研究发现，早期PCI可以改善NSTEMI罪犯动脉闭塞患者的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annali italiani di chirurgia 医学-外科

CiteScore

0.90

自引率

12.50%

发文量

116

审稿时长

>12 weeks

期刊介绍： Annali Italiani di Chirurgia is a bimonthly journal and covers all aspects of surgery:elective, emergency and experimental surgery, as well as problems involving technology, teaching, organization and forensic medicine. The articles are published in Italian or English, though English is preferred because it facilitates the international diffusion of the journal (v.Guidelines for Authors and Norme per gli Autori). The articles published are divided into three main sections:editorials, original articles, and case reports and innovations.