Intraoperative parathyroid hormone monitoring in parathyroidectomy: Predicting cure and recurrence in tertiary hyperparathyroidism - systematic review

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY American Journal of Otolaryngology Pub Date : 2025-03-11 DOI:10.1016/j.amjoto.2025.104609

Kevin P.J. Finnegan, Gavin P. Dowling, Sami Abd El Wahab , Arnold D.K. Hill

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引用次数: 0

Abstract

Objective

The aim of this systematic review was to investigate the value of intraoperative parathyroid hormone (IOPTH) monitoring in parathyroidectomy for tertiary hyperparathyroidism (THPT) to predict cure and recurrence.

Data sources

Ovid, Embase, EBSCO Host, Citation Checking.

Methods

This study was performed in accordance with PRISMA guidelines. A systematic search of the literature was conducted to identify studies evaluating IOPTH monitoring in patients with THPT. Only studies addressing THPT with documented use of IOPTH in their surgery were included.

Results

In 11 of the 18 studies included in this review IOPTH monitoring influenced the surgery by identifying insufficient resection or ectopic/supernumerary glands necessitating further resection to cure patients. Rates of recurrence were absent or minimal in patients who achieved appropriate IOPTH drops at specified time intervals.

Conclusion

IOPTH monitoring is a useful adjunct to prevent insufficient resection of hyperplastic glands and to identify ectopic/supernumerary glands. Median PTH drop at specified time intervals can help predict cure and recurrence in parathyroidectomy for THPT.

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来源期刊

American Journal of Otolaryngology 医学-耳鼻喉科学

CiteScore

4.40

自引率

4.00%

发文量

378

审稿时长

41 days

期刊介绍： Be fully informed about developments in otology, neurotology, audiology, rhinology, allergy, laryngology, speech science, bronchoesophagology, facial plastic surgery, and head and neck surgery. Featured sections include original contributions, grand rounds, current reviews, case reports and socioeconomics.