Effectiveness of Chamomile in Reducing the Incidence and Severity of Nausea and Vomiting After Middle Ear Surgery: A Triple-Blind Randomized Study.

Q2 Medicine Anesthesiology and Pain Medicine Pub Date : 2025-01-07 eCollection Date: 2024-12-01 DOI:10.5812/aapm-153566
Maryam Sarkhosh, Ehsan Rajabi Visroodi, Hamidreza Samaee, Motahareh Farhadi, Parisa Moradimajd
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Abstract

Background: Nausea and vomiting are among the most common complications after surgery.

Objectives: The aim of this study was to investigate the effectiveness of chamomile in reducing the incidence and severity of nausea and vomiting after middle ear surgery.

Methods: A total of 110 patients who met the inclusion criteria were randomly assigned to either the chamomile or placebo group. Group A consumed chamomile drops (500 mg), while group B consumed cornstarch with 30 mL of water, one hour before surgery. The severity of nausea and frequency of vomiting were recorded at recovery (time of zero), 1, 2, 4, and 6 hours after surgery using the Rhodes Index. Data were analyzed using SPSS v.21 software, paired t-tests, and chi-square tests.

Results: A total of 110 patients were included, with an average age of 36.14 ± 10.3 years (group A) and 34.28 ± 13.3 years (group B). There was no statistically significant difference between the chamomile and placebo groups in terms of the severity of nausea and the frequency of vomiting immediately after recovery (time of zero), 1, 2, and 6 hours after surgery (P > 0.05). However, 4 hours post-surgery, the severity of nausea in the chamomile group was lower than in the placebo group, and a statistically significant difference was observed between the two groups (P = 0.03). No gastrointestinal side effects were reported.

Conclusions: Based on the results of this study, chamomile can be used to reduce nausea and vomiting after middle ear surgery, given its availability and low cost.

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甘菊降低中耳手术后恶心呕吐发生率和严重程度的有效性:一项三盲随机研究。
背景:恶心和呕吐是手术后最常见的并发症之一。目的:本研究的目的是探讨洋甘菊对减少中耳手术后恶心和呕吐的发生率和严重程度的有效性。方法:总共110例符合纳入标准的患者被随机分配到洋甘菊组或安慰剂组。A组在手术前一小时服用洋甘菊滴剂(500毫克),B组在手术前一小时服用玉米淀粉和30毫升水。术后恢复(0小时)、1小时、2小时、4小时和6小时用Rhodes指数记录恶心严重程度和呕吐频率。数据分析采用SPSS v.21软件,配对t检验和卡方检验。结果:共纳入110例患者,平均年龄分别为36.14±10.3岁(A组)和34.28±13.3岁(B组)。洋甘菊组与安慰剂组在恢复后立即(0时间)、术后1、2、6小时的恶心严重程度和呕吐次数方面,差异均无统计学意义(P < 0.05)。但术后4小时,洋甘菊组恶心程度低于安慰剂组,两组比较差异有统计学意义(P = 0.03)。没有胃肠道副作用的报道。结论:基于本研究的结果,考虑到洋甘菊的可获得性和低成本,可以用于减少中耳手术后的恶心和呕吐。
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来源期刊
Anesthesiology and Pain Medicine
Anesthesiology and Pain Medicine Medicine-Anesthesiology and Pain Medicine
CiteScore
4.60
自引率
0.00%
发文量
49
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