Management of perforated peptic ulcer: What you need to know.

IF 3.7 2区 医学 Q2 CRITICAL CARE MEDICINE Journal of Trauma and Acute Care Surgery Pub Date : 2025-07-01 Epub Date: 2025-03-17 DOI:10.1097/TA.0000000000004561
Samir Rasslan, Raul Coimbra, Roberto Rasslan, Edivaldo M Utiyama
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Abstract

Abstract: Despite therapeutic advancements and the significant efficacy of medical management, peptic ulcer disease still affects millions of people. Elective surgical treatment, once a common intervention in General Surgery departments, is now nearly obsolete. Surgical treatment is reserved solely for complications, which occur in approximately 10% to 20% of cases. Perforation is the most common indication for surgery in peptic ulcer disease and accounts for nearly 40% of deaths from the disease. Treatment success depends on various factors, with early diagnosis and immediate surgical intervention being highlighted. Perforation is associated with a high incidence of morbidity and mortality. This article aims to analyze the different aspects related to the treatment of perforated peptic ulcers and define the best therapeutic approaches.

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穿孔性消化性溃疡的处理:你需要知道的。
摘要:尽管治疗取得了进步,医疗管理也取得了显著成效,但消化性溃疡疾病仍然影响着数百万人。选择性手术治疗,曾经是普通外科的一种常见的干预措施,现在几乎已经过时了。手术治疗仅适用于并发症,并发症发生率约为10%至20%。穿孔是消化性溃疡最常见的手术指征,占该疾病死亡人数的近40%。治疗成功取决于多种因素,早期诊断和立即手术干预是重点。穿孔与高发病率和高死亡率有关。本文旨在分析与穿孔性消化性溃疡治疗相关的不同方面,并确定最佳治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.00
自引率
11.80%
发文量
637
审稿时长
2.7 months
期刊介绍: The Journal of Trauma and Acute Care Surgery® is designed to provide the scientific basis to optimize care of the severely injured and critically ill surgical patient. Thus, the Journal has a high priority for basic and translation research to fulfill this objectives. Additionally, the Journal is enthusiastic to publish randomized prospective clinical studies to establish care predicated on a mechanistic foundation. Finally, the Journal is seeking systematic reviews, guidelines and algorithms that incorporate the best evidence available.
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