Risk for Unplanned Pregnancy Among Survivors of Childhood Cancer

IF 2.3 3区 医学 Q2 HEMATOLOGY Pediatric Blood & Cancer Pub Date : 2025-03-17 DOI:10.1002/pbc.31653
Brooke Cherven, Kayla Fitch, Lauren Quast Esposito, Ebonee Harris, Karen Burns, Jenna Demedis, Holly Hoefgen, Ann Mertens, James L. Klosky
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Abstract

The purpose of this study was to identify factors associated with risk for unplanned pregnancy in sexually active female survivors using self-report survey data. Risk for unplanned pregnancy was defined as using less effective/no contraception while also not desiring pregnancy. Of N = 160 participants (age 24.0 ± 3.1 years), 33.1% were at-risk for unplanned pregnancy. On multivariable analysis, participants were less likely to be categorized at-risk for unplanned pregnancy if they reported diagnosis of ovarian failure/premature menopause (odds ratio [OR] 0.16, 95% confidence interval [CI] 0.02–0.72, p = 0.032), greater concerns about fertility (OR 0.59, 95%CI 0.43–0.80, p = 0.001), and religious identity of agnostic/atheist (compared with Christian, OR 0.10, 95%CI 0.01–0.41, p = 0.005).

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儿童癌症幸存者意外怀孕的风险
本研究的目的是利用自我报告调查数据,确定与性活跃女性幸存者意外怀孕风险相关的因素。意外怀孕的风险被定义为在不希望怀孕的情况下使用效果较差或没有避孕措施。在160名参与者(年龄24.0±3.1岁)中,33.1%的人有意外怀孕的风险。在多变量分析中,如果参与者报告了卵巢功能衰竭/过早绝经的诊断(比值比[OR] 0.16, 95%可信区间[CI] 0.02-0.72, p = 0.032),更关注生育(比值比[OR] 0.59, 95%CI 0.43-0.80, p = 0.001),以及宗教身份为不可知论者/无神论者(与基督徒相比,比值比[OR] 0.10, 95%CI 0.01-0.41, p = 0.005),则他们被归类为有意外怀孕风险的可能性较小。
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来源期刊
Pediatric Blood & Cancer
Pediatric Blood & Cancer 医学-小儿科
CiteScore
4.90
自引率
9.40%
发文量
546
审稿时长
1.5 months
期刊介绍: Pediatric Blood & Cancer publishes the highest quality manuscripts describing basic and clinical investigations of blood disorders and malignant diseases of childhood including diagnosis, treatment, epidemiology, etiology, biology, and molecular and clinical genetics of these diseases as they affect children, adolescents, and young adults. Pediatric Blood & Cancer will also include studies on such treatment options as hematopoietic stem cell transplantation, immunology, and gene therapy.
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