Exploring the predictive value of complete blood count inflammatory parameters in early pregnancy for missed abortion.

Abstract

IntroductionThe aim of this study was to assess the potential role of complete blood count (CBC) inflammatory parameters in the diagnosis and management of missed abortions during early pregnancy through the analysis of their values.MethodsThe case group for our study comprised 500 instances of missed abortions at Fujian Provincial Maternal and Child Health Hospital from May 2023 to May 2024, whereas the control group consisted of 500 healthy women who did not experience delivery-related complications during this timeframe. We utilized SPSS version 25 software to conduct a retrospective analysis of factors, including age, BMI, gravidity, parity, neutrophil count, lymphocyte count, platelet count, mean platelet volume, platelet distribution width, and prothrombin time.ResultsThe age and gravidity of patients in the missed abortion group were higher than those in the normal pregnancy group, with a statistically significant difference. There were no significant differences in the platelet count, mean platelet volume, platelet distribution width, neutrophil count, or prothrombin time between the two groups. But the lymphocyte count was significantly lower in the missed abortion pregnancies. The area under the ROC curve for the lymphocyte count was 0.654, indicating its diagnostic value.ConclusionAlthough the lymphocyte count can offer some predictive value in detecting missed abortion, its diagnostic accuracy is limited. Other inflammatory parameters don't yield any predictive information regarding miscarriage retention.