Butter and Beef Tolerance in Children with IgE-Mediated Cow's Milk Allergy.

IF 0.8 4区 医学 Q4 ALLERGY Pediatric Allergy Immunology and Pulmonology Pub Date : 2025-06-01 Epub Date: 2025-03-19 DOI:10.1089/ped.2024.0128
Stefano Miceli Sopo, Matteo Di Toro Mammarella, Mariannita Gelsomino, Francesco Mastellone, Marta Barbato, Bruno Miceli Sopo, Giulia Bersani
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Abstract

Background: Butter and beef are often prejudicially forbidden for children affected by IgE-mediated cow's milk allergy (IgE-CMA). Methods: Children with IgE-CMA underwent prick-by-prick (PbP) test with clarified butter and normal butter, raw and cooked beef. In case of positivity of the PbP, an oral food challenge (OFC) with that food was proposed. Results: Thirty children with IgE-CMA were enrolled. Twenty-five (83%) introduced clarified butter into their diet; the remaining 5 did not want to do so. Fifteen patients (50%) were authorized to introduce normal butter into their diet; 1 patient (3%) was allergic to normal butter; for 14 patients (47%), allergy to normal butter remained uncertain. All 30 patients enrolled ate cooked beef without any problem. No one introduced raw or undercooked beef in his own diet for reasons of hygiene and taste. Conclusions: It is advisable to perform a PbP and eventually an OFC with normal butter, clarified butter, and cooked beef in any child affected by IgE-CMA.

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ige介导的牛奶过敏儿童对黄油和牛肉的耐受性。
背景:对于受ige介导的牛奶过敏(IgE-CMA)影响的儿童,通常禁止使用黄油和牛肉。方法:对IgE-CMA患儿用澄清黄油、正常黄油、生牛肉和熟牛肉进行PbP试验。在PbP阳性的情况下,建议使用该食物进行口服食物挑战(OFC)。结果:30例IgE-CMA患儿入组。25个国家(83%)在饮食中加入了澄清黄油;剩下的5个不愿意这样做。15名患者(50%)被授权在饮食中加入普通黄油;1例(3%)对普通黄油过敏;14名患者(47%)对普通黄油过敏仍不确定。所有30名患者都吃了煮熟的牛肉,没有任何问题。没有人出于卫生和口味的原因在自己的饮食中引入生牛肉或未煮熟的牛肉。结论:建议对任何受IgE-CMA影响的儿童进行PbP检查,并最终用正常黄油、澄清黄油和熟牛肉进行OFC检查。
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来源期刊
CiteScore
2.00
自引率
0.00%
发文量
23
审稿时长
>12 weeks
期刊介绍: Pediatric Allergy, Immunology, and Pulmonology is a peer-reviewed journal designed to promote understanding and advance the treatment of respiratory, allergic, and immunologic diseases in children. The Journal delivers original translational, clinical, and epidemiologic research on the most common chronic illnesses of children—asthma and allergies—as well as many less common and rare diseases. It emphasizes the developmental implications of the morphological, physiological, pharmacological, and sociological components of these problems, as well as the impact of disease processes on families. Pediatric Allergy, Immunology, and Pulmonology coverage includes: -Functional and genetic immune deficiencies- Interstitial lung diseases- Both common and rare respiratory, allergic, and immunologic diseases- Patient care- Patient education research- Public health policy- International health studies
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